KP-23172

Modify Date: 2025-08-24 21:42:48

KP-23172 Structure
KP-23172 structure
 Common Name KP-23172
CAS Number 331253-86-2 Molecular Weight 224.17800
Density N/A Boiling Point N/A
Molecular Formula C10H4N6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KP-23172


KP-23172 is a PI3-K/Akt pathway inhibitor extracted from patent US7196083[1].

 Names

Name 10H-Indeno[2,1-e]tetrazolo[1,5-b][1,2,4]triazin-10-one
Synonym More Synonyms

 KP-23172 Biological Activity

Description KP-23172 is a PI3-K/Akt pathway inhibitor extracted from patent US7196083[1].
Related Catalog
Target

PI3-K

Akt

In Vitro KP-23172 (10 µM; 60 min) significantly augments NRP-induced apoptosis [1].
References

[1]. Xi RG, et al. Roles of PI3-K/Akt pathways in nanoparticle realgar powders-induced apoptosis in U937 cells. Acta Pharmacol Sin. 2008 Mar;29(3):355-63.

 Chemical & Physical Properties

Molecular Formula C10H4N6O
Molecular Weight 224.17800
Exact Mass 224.04500
PSA 85.93000
LogP 0.12570
InChIKey DPANHMGWPXVBQI-UHFFFAOYSA-N
SMILES O=C1c2ccccc2-c2nc3nnnn3nc21
Storage condition -20℃

 Safety Information

 Synthetic Route

tetrazole-1,5-diamine structure

tetrazole-1,5-d...

CAS#:2165-21-1

Ninhydrin structure

Ninhydrin

CAS#:485-47-2

~%

kp372-1 structure

kp372-1

CAS#:329710-24-9

KP-23172 Structure

KP-23172

CAS#:331253-86-2

Literature: Hybrigenics S.A. Patent: EP1918292 A1, 2008 ; Location in patent: Page/Page column 18-19 ; EP 1918292 A1

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

p-Dimethylaminophenyl-isopropyl-sulfid
PDK1/Akt/Flt Dual Pathway Inhibitor
Benzenamine,N,N-dimethyl-4-[(1-methylethyl)thio]
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Chemsrc provides KP-23172(CAS#:331253-86-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of KP-23172 are included as well.>> amp version: KP-23172

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