Glycolate oxidase-IN-1
Modify Date: 2025-08-26 13:51:08
Glycolate oxidase-IN-1 structure
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Common Name | Glycolate oxidase-IN-1 | ||
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| CAS Number | 330977-65-6 | Molecular Weight | 232.19 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H8O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Glycolate oxidase-IN-1Glycolate oxidase-IN-1(compound 26), a salicylic acid derivative, is a glycolate oxidase (GO) inhibitor with an IC50 of 38.2 μM. Glycolate oxidase-IN-1 has the ability to reduce oxalate production in hyperoxalate hepatocytes and can be used in the study of primary hyperoxaluria type 1 (PH1)[1]. |
| Name | Glycolate oxidase-IN-1 |
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| Description | Glycolate oxidase-IN-1(compound 26), a salicylic acid derivative, is a glycolate oxidase (GO) inhibitor with an IC50 of 38.2 μM. Glycolate oxidase-IN-1 has the ability to reduce oxalate production in hyperoxalate hepatocytes and can be used in the study of primary hyperoxaluria type 1 (PH1)[1]. |
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| Related Catalog | |
| In Vitro | Glycolate oxidase-IN-1(compound 26)(0-12.5 μM, 48 h)处理小鼠肝细胞，在浓度为 6.25 μM 时，排出的草酸盐水平显着降低 67.3 ± 32%。在 12.5 μM 的浓度下，处理 24 小时和 48 小时后分别减少105.8 ± 29.2% 和 62.3 ± 24.4%，且没有任何细胞毒性[1]。 |
| References |
| Molecular Formula | C12H8O5 |
|---|---|
| Molecular Weight | 232.19 |
| InChIKey | CYEKBFDCMORSFM-UHFFFAOYSA-N |
| SMILES | O=Cc1ccc(-c2ccc(O)c(C(=O)O)c2)o1 |