2005454-12-4

2005454-12-4 structure

Name: PD1-PDL1-IN 1
Chemical Name: PD1 Inhbitor, Aurigene Cmpd 16
CAS Number: 2005454-12-4
Molecular Formula: C₁₄H₂₃N₇O₆
Molecular Weight: 385.38
Catalog: Signaling Pathways Immunology/Inflammation PD-1/PD-L1
Create Date: 2018-06-05 16:41:58
Modify Date: 2026-07-03 21:14:00
PD1-PDL1-IN 1 is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 is useful as immune modulator[1].

Name	PD1 Inhbitor, Aurigene Cmpd 16

Description	PD1-PDL1-IN 1 is a potent programmed cell death 1 (PD-1) inhibitor. PD1-PDL1-IN 1 is useful as immune modulator[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1 Research Areas >> Inflammation/Immunology
In Vitro	PD-1 (or Programmed Cell Death 1 or PDCD1) is a ~55kD type I membrane glycoprotein and is a receptor of the CD28 superfamily that negatively regulates T cell antigen receptor signalling by interacting with the specific ligands. PD-1 is suggested to play significant role in the maintenance of self-tolerance[1].
References	[1]. Pottayil Govindan Nair Sasikumar , et al. 3-substituted-1,2,4-oxadiazole and thiadiazole compounds as immunomodulators. WO2016142886A2.