AGX51

Modify Date: 2024-01-20 17:18:03

AGX51 Structure
AGX51 structure
Common Name AGX51
CAS Number 330834-54-3 Molecular Weight 431.52
Density N/A Boiling Point N/A
Molecular Formula C27H29NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AGX51


AGX51 is a first-in-class pan-Id (inhibitors of DNA-binding/differentiation proteins) antagonist and degrader. AGX51 inhibits the Id1-E47 interaction, leading to ubiquitin-mediated degradation of Ids, cell growth arrest, and reduces viability. AGX51 inhibits pathologic ocular neovascularization[1].

 Names

Name AGX51

 AGX51 Biological Activity

Description AGX51 is a first-in-class pan-Id (inhibitors of DNA-binding/differentiation proteins) antagonist and degrader. AGX51 inhibits the Id1-E47 interaction, leading to ubiquitin-mediated degradation of Ids, cell growth arrest, and reduces viability. AGX51 inhibits pathologic ocular neovascularization[1].
Related Catalog
References

[1]. Wojnarowicz PM, et al. A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization. Cell Rep. 2019 Oct 1;29(1):62-75.e7.

 Chemical & Physical Properties

Molecular Formula C27H29NO4
Molecular Weight 431.52

 Safety Information

Hazard Codes Xi
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