AGX51

Names

[ Name ]:
AGX51

Biological Activity

[Description]:

AGX51 is a first-in-class pan-Id (inhibitors of DNA-binding/differentiation proteins) antagonist and degrader. AGX51 inhibits the Id1-E47 interaction, leading to ubiquitin-mediated degradation of Ids, cell growth arrest, and reduces viability. AGX51 inhibits pathologic ocular neovascularization[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Wojnarowicz PM, et al. A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization. Cell Rep. 2019 Oct 1;29(1):62-75.e7.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₂₉NO₄

[ Molecular Weight ]:
431.52

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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