AKTide-2T TFA

Modify Date: 2025-09-10 17:46:40

AKTide-2T TFA structure	Common Name	AKTide-2T TFA
	CAS Number	324029-01-8	Molecular Weight	1715.87000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₇₄H₁₁₄N₂₈O₂₀	Melting Point	153-156ºC
	MSDS	N/A	Flash Point	N/A

Use of AKTide-2T TFA

AKTide-2T is an excellent in vitro substrate for AKT and shows competitive inhibition of histone H2B phosphorylation with a Ki of 12 nM. AKTide-2T mimics the optimal phosphorylation sequence of Akt and is an inhibitory peptide with the wildtype AKTide lacking Thr in the S22 position[1].

Name	AKTide-2T
Synonym	More Synonyms

Description	AKTide-2T is an excellent in vitro substrate for AKT and shows competitive inhibition of histone H2B phosphorylation with a Ki of 12 nM. AKTide-2T mimics the optimal phosphorylation sequence of Akt and is an inhibitory peptide with the wildtype AKTide lacking Thr in the S22 position[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> PI3K/Akt/mTOR >> Akt
Target	Akt
In Vitro	AKTide-2T mimics the optimal phosphorylation sequence of Akt, and inhibits Akt phosphorylated Hsp27 by addition of 20 μM Akt inhibitory peptide[1].
References	[1]. T Obata,et al. Peptide and protein library screening defines optimal substrate motifs for AKT/PKB. J Biol Chem. 2000 Nov 17;275(46):36108-15. [2]. Madhavi J Rane, et al. Heat shock protein 27 controls apoptosis by regulating Akt activation. J Biol Chem. 2003 Jul 25;278(30):27828-35.

Melting Point	153-156ºC
Molecular Formula	C₇₄H₁₁₄N₂₈O₂₀
Molecular Weight	1715.87000
Exact Mass	1714.88000
PSA	808.69000
LogP	0.70630
Storage condition	-20°C