Medicarpin

Modify Date: 2024-01-02 20:17:56

Medicarpin Structure
Medicarpin structure
 Common Name Medicarpin
CAS Number 32383-76-9 Molecular Weight 270.280
Density 1.3±0.1 g/cm3 Boiling Point 418.8±45.0 °C at 760 mmHg
Molecular Formula C16H14O4 Melting Point 127.5-128.5°
MSDS N/A Flash Point 207.1±28.7 °C

 Use of Medicarpin


Medicarpin is a flavonoid isolated from Medicago sativa. Medicarpin induces apoptosis and overcome multidrug resistance in leukemia P388 cells by modulating P-gp-mediated efflux of drugs[1].

 Names

Name (-)-medicarpin
Synonym More Synonyms

 Medicarpin Biological Activity

Description Medicarpin is a flavonoid isolated from Medicago sativa. Medicarpin induces apoptosis and overcome multidrug resistance in leukemia P388 cells by modulating P-gp-mediated efflux of drugs[1].
Related Catalog
In Vitro Medicarpin (90 µM; for 48 h) triggers apoptosis in sensitive as well as multidrug resistant P388 cells. P-glycoprotein-expressing P388/DOX cells does not show resistance to medicarpin (IC50≈90 µM for P388 and P388/DOX cells)[1].
References

[1]. Grégory Gatouillat, et al. Medicarpin and millepurpan, two flavonoids isolated from Medicago sativa, induce apoptosis and overcome multidrug resistance in leukemia P388 cells. medicine. 2015 Dec 1;22(13):1186-94.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 418.8±45.0 °C at 760 mmHg
Melting Point 127.5-128.5°
Molecular Formula C16H14O4
Molecular Weight 270.280
Flash Point 207.1±28.7 °C
Exact Mass 270.089203
PSA 47.92000
LogP 2.72
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.630

 Safety Information

Hazard Codes Xi

 Synthetic Route

(2R,3S)-2,7,4'-trihydroxyisoflavanone structure

(2R,3S)-2,7,4'-...

CAS#:131887-80-4

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Medicarpin Structure

Medicarpin

CAS#:32383-76-9
Literature: Akashi, Tomoyoshi; VanEtten, Hans D.; Sawada, Yuji; Wasmann, Catherine C.; Uchiyama, Hiroshi; Ayabe, Shin-ichi Phytochemistry, 2006 , vol. 67, # 23 p. 2525 - 2530
N/A structure

N/A

CAS#:1891-01-6

~%

Medicarpin Structure

Medicarpin

CAS#:32383-76-9

(6aS,11aS)-9-methoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromen-3-ol structure

(6aS,11aS)-9-me...

CAS#:33983-39-0
Literature: Goel, Atul; Kumar, Amit; Hemberger, Yasmin; Raghuvanshi, Ashutosh; Jeet, Ram; Tiwari, Govind; Knauer, Michael; Kureel, Jyoti; Singh, Anuj K.; Gautam, Abnish; Trivedi, Ritu; Singh, Divya; Bringmann, Gerhard Organic and Biomolecular Chemistry, 2012 , vol. 10, # 48 p. 9583 - 9592
2'-Hydroxyformononetin structure

2'-Hydroxyformo...

CAS#:1890-99-9

~%

Medicarpin Structure

Medicarpin

CAS#:32383-76-9

(6aS,11aS)-9-methoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromen-3-ol structure

(6aS,11aS)-9-me...

CAS#:33983-39-0
Literature: Goel, Atul; Kumar, Amit; Hemberger, Yasmin; Raghuvanshi, Ashutosh; Jeet, Ram; Tiwari, Govind; Knauer, Michael; Kureel, Jyoti; Singh, Anuj K.; Gautam, Abnish; Trivedi, Ritu; Singh, Divya; Bringmann, Gerhard Organic and Biomolecular Chemistry, 2012 , vol. 10, # 48 p. 9583 - 9592
Resorcine structure

Resorcine

CAS#:108-46-3

~%

Medicarpin Structure

Medicarpin

CAS#:32383-76-9

(6aS,11aS)-9-methoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromen-3-ol structure

(6aS,11aS)-9-me...

CAS#:33983-39-0
Literature: Goel, Atul; Kumar, Amit; Hemberger, Yasmin; Raghuvanshi, Ashutosh; Jeet, Ram; Tiwari, Govind; Knauer, Michael; Kureel, Jyoti; Singh, Anuj K.; Gautam, Abnish; Trivedi, Ritu; Singh, Divya; Bringmann, Gerhard Organic and Biomolecular Chemistry, 2012 , vol. 10, # 48 p. 9583 - 9592
Medicarpin Structure

Medicarpin

CAS#:32383-76-9

~%

Medicarpin Structure

Medicarpin

CAS#:32383-76-9

(6aS,11aS)-9-methoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromen-3-ol structure

(6aS,11aS)-9-me...

CAS#:33983-39-0
Literature: Goel, Atul; Kumar, Amit; Hemberger, Yasmin; Raghuvanshi, Ashutosh; Jeet, Ram; Tiwari, Govind; Knauer, Michael; Kureel, Jyoti; Singh, Anuj K.; Gautam, Abnish; Trivedi, Ritu; Singh, Divya; Bringmann, Gerhard Organic and Biomolecular Chemistry, 2012 , vol. 10, # 48 p. 9583 - 9592
(2,4-Dimethoxyphenyl)acetic acid structure

(2,4-Dimethoxyp...

CAS#:6496-89-5

~%

Medicarpin Structure

Medicarpin

CAS#:32383-76-9

(6aS,11aS)-9-methoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromen-3-ol structure

(6aS,11aS)-9-me...

CAS#:33983-39-0
Literature: Goel, Atul; Kumar, Amit; Hemberger, Yasmin; Raghuvanshi, Ashutosh; Jeet, Ram; Tiwari, Govind; Knauer, Michael; Kureel, Jyoti; Singh, Anuj K.; Gautam, Abnish; Trivedi, Ritu; Singh, Divya; Bringmann, Gerhard Organic and Biomolecular Chemistry, 2012 , vol. 10, # 48 p. 9583 - 9592
2,7-dihydroxy-4'-methoxyisoflavanone structure

2,7-dihydroxy-4...

CAS#:770722-02-6

~%

Medicarpin Structure

Medicarpin

CAS#:32383-76-9
Literature: Akashi, Tomoyoshi; VanEtten, Hans D.; Sawada, Yuji; Wasmann, Catherine C.; Uchiyama, Hiroshi; Ayabe, Shin-ichi Phytochemistry, 2006 , vol. 67, # 23 p. 2525 - 2530
Formononetin structure

Formononetin

CAS#:485-72-3

~%

Medicarpin Structure

Medicarpin

CAS#:32383-76-9
Literature: Akashi, Tomoyoshi; VanEtten, Hans D.; Sawada, Yuji; Wasmann, Catherine C.; Uchiyama, Hiroshi; Ayabe, Shin-ichi Phytochemistry, 2006 , vol. 67, # 23 p. 2525 - 2530

 Synonyms

l-3-Hydroxy-9-methoxypterocarpan
6H-Benzofuro[3,2-c][1]benzopyran-3-ol, 6a,11a-dihydro-9-methoxy-, (6aR-cis)-
UNII-6TX086I6IG
(-)-3-Hydroxy-9-methoxypterocarpan
3-hydroxy-9-methoxypterocarpan
Demethylhomopterocarpin
Medicarpin
6H-Benzofuro[3,2-c][1]benzopyran-3-ol, 6a,11a-dihydro-9-methoxy-, (6aR,11aR)-
(6aR-cis)-6a,11a-Dihydro-9-methoxy-6H-benzofuro[3,2-c][1]benzopyran-3-ol
(6aR,11aR)-9-Methoxy-6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromen-3-ol
Medicarpin, (-)-
demethylhomopterocarpan
Top Suppliers:I want be here
  • BioBioPha
  • China
  • Product Name: Medicarpin
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  • DC Chemicals Limited
  • China
  • Product Name: Medicarpin
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  • Purity: 98.0%
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Related Compounds: More...
Medicarpin
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52766-70-8
medicarpin
33983-40-3
(6aS,11aS)-4-(5-Hydroxy-6-methoxy-3-phenyl-1-benzofuran-2-ylmethyl)medicarpin
164124-45-2
Medicarpin
51828-10-5
Chemsrc provides Medicarpin(CAS#:32383-76-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Medicarpin are included as well.>> amp version: Medicarpin

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