ICA-105574
Modify Date: 2025-08-25 18:06:03
ICA-105574 structure
|
Common Name | ICA-105574 | ||
|---|---|---|---|---|
| CAS Number | 316146-57-3 | Molecular Weight | 334.33 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H14N2O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
Use of ICA-105574ICA-105574 is a potent and efficacious hERG channel activator. The primary mechanism by which ICA-105574 potentiates hERG channel activity is by removing hERG channel inactivation. ICA-105574 steeply potentiates current amplitudes more than 10-fold with an EC50 value of 0.5 +/- 0.1 μM and a Hill slope (n(H)) of 3.3 +/- 0.2[1]. |
| Name | 3-nitro-N-(4-phenoxyphenyl)benzamide |
|---|---|
| Synonym | More Synonyms |
| Description | ICA-105574 is a potent and efficacious hERG channel activator. The primary mechanism by which ICA-105574 potentiates hERG channel activity is by removing hERG channel inactivation. ICA-105574 steeply potentiates current amplitudes more than 10-fold with an EC50 value of 0.5 +/- 0.1 μM and a Hill slope (n(H)) of 3.3 +/- 0.2[1]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C19H14N2O4 |
|---|---|
| Molecular Weight | 334.33 |
| Exact Mass | 334.09500 |
| PSA | 84.15000 |
| LogP | 5.23560 |
| InChIKey | GDWKBKTVROCPNZ-UHFFFAOYSA-N |
| SMILES | O=C(Nc1ccc(Oc2ccccc2)cc1)c1cccc([N+](=O)[O-])c1 |
| Symbol |
GHS07, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H317-H319-H400 |
| Precautionary Statements | P273-P280-P305 + P351 + P338 |
| RIDADR | UN 3077 9 / PGIII |
| 3-nitro-N-(4-phenoxyphenyl)-benzamide |
| 3-NITRO-N-(4-PHENOXYPHENYL)BENZAMIDE |
| F1107-0308 |