migrastatin
Modify Date: 2024-01-09 10:17:19
migrastatin structure
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Common Name | migrastatin | ||
|---|---|---|---|---|
| CAS Number | 314245-65-3 | Molecular Weight | 489.60100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H39NO7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of migrastatinMigrastatin is a typical Fascin1 inhibitor. Migrastatin is isolated from a cultured broth of Streptomyces sp. MK929-43F1. Migrastatin inhibits tumor cell migration[1][2]. |
| Name | migrastatin |
|---|---|
| Synonym | More Synonyms |
| Description | Migrastatin is a typical Fascin1 inhibitor. Migrastatin is isolated from a cultured broth of Streptomyces sp. MK929-43F1. Migrastatin inhibits tumor cell migration[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Fascin1[1] |
| In Vitro | Migrastatin (100 μM) leads to the disorganization of the bundles. Migrastatin (100 μM; HCT-116 and DLD-1 cells) prevents cell migration[1]. |
| References |
| Molecular Formula | C27H39NO7 |
|---|---|
| Molecular Weight | 489.60100 |
| Exact Mass | 489.27300 |
| PSA | 122.49000 |
| LogP | 3.46690 |
| InChIKey | OGYMUMAKGYYNHV-IJMHZYIBSA-N |
| SMILES | COC1C=CCCC=CC(=O)OC(C(C)C(=O)CCCC2CC(=O)NC(=O)C2)C(C)=CC(C)C1O |
| Hazard Codes | Xi |
|---|
| Migrastatin |
| 4-[(5S)-5-[(2R,3Z,5R,6S,7S,8E,12E)-6-hydroxy-7-methoxy-3,5-dimethyl-14-oxo-1-oxacyclotetradeca-3,8,12-trien-2-yl]-4-oxohexyl]piperidine-2,6-dione |
| 4-{(5S)-5-[(2R,3Z,5R,6S,7S,8E,12E)-6-hydroxy-7-methoxy-3,5-dimethyl-14-oxooxacyclotetradeca-3,8,12-trien-2-yl]-4-oxohexyl}piperidine-2,6-dione |