Mycro1
Modify Date: 2024-04-03 19:18:36
Mycro1 structure
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Common Name | Mycro1 | ||
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| CAS Number | 313987-85-8 | Molecular Weight | 432.42 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H15F3N4O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Mycro1Mycro1 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC50 value of 30 μM for the inhibition of Myc/Max DNA binding activity. Mycro1 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation[1]. |
| Name | Mycro1 |
|---|
| Description | Mycro1 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC50 value of 30 μM for the inhibition of Myc/Max DNA binding activity. Mycro1 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation[1]. |
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| Related Catalog | |
| In Vitro | Mycro1(10 or 20 μM, 7 days)可以抑制 C-Myc 依赖细胞系 U-2OS、MCF-7、Raji 和 NIH/3T3 的增殖，不会抑制 C-Myc 独立癌细胞株 PC-12 的增殖。Mycro1 在 10 μM 时可以显著抑制 c- myc 诱导的基因转录，在 20 μM 时可以选择性减少 c- myc 转化Rat1a细胞的非锚定生长[1]。 |
| References |
| Molecular Formula | C20H15F3N4O2S |
|---|---|
| Molecular Weight | 432.42 |