Reversan
Reversan structure
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Common Name | Reversan | ||
|---|---|---|---|---|
| CAS Number | 313397-13-6 | Molecular Weight | 441.52 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H27N5O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of ReversanReversan (CBLC4H10) is a potent and nontoxic multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (Pgp) inhibitor[1][2]. |
| Name | N-(3-morpholin-4-ylpropyl)-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | Reversan (CBLC4H10) is a potent and nontoxic multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (Pgp) inhibitor[1][2]. |
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| Related Catalog | |
| Target |
Multidrug resistance-associated protein 1, P-glycoprotein[1] |
| References |
| Molecular Formula | C26H27N5O2 |
|---|---|
| Molecular Weight | 441.52 |
| Exact Mass | 441.21600 |
| PSA | 75.25000 |
| LogP | 4.02810 |
| Storage condition | 2-8℃ |
| RIDADR | NONH for all modes of transport |
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Novel perspectives for hepatitis A virus therapy revealed by comparative analysis of hepatitis C virus and hepatitis A virus RNA replication.
Hepatology 62 , 397-408, (2015) Hepatitis A virus (HAV) and hepatitis C virus (HCV) are two positive-strand RNA viruses sharing a similar biology, but causing opposing infection outcomes, with HAV always being cleared and HCV establ... |
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Tumor cells chronically treated with a trastuzumab-maytansinoid antibody-drug conjugate develop varied resistance mechanisms but respond to alternate treatments.
Mol. Cancer Ther. 14 , 952-63, (2015) Antibody-drug conjugates (ADC) are emerging as clinically effective therapy. We hypothesized that cancers treated with ADCs would acquire resistance mechanisms unique to immunoconjugate therapy and th... |
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ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux.
J. Natl. Cancer Inst. 103 , 1236-51, (2011) Although the prognostic value of the ATP-binding cassette, subfamily C (ABCC) transporters in childhood neuroblastoma is usually attributed to their role in cytotoxic drug efflux, certain observations... |
| N-[3-(4-morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide |
| Reversan |
| CBLC4H10 |
| HMS2467O12 |
| CBLC4H10 N-[3-(4-Morpholinyl)propyl]-5,7-diphenyl-pyrazolo[1,5-a]pyrimidine-3-carboxamide |