PROTO-1

Modify Date: 2024-01-11 13:51:02

PROTO-1 structure	Common Name	PROTO-1
	CAS Number	312951-85-2	Molecular Weight	378.876
	Density	1.4±0.1 g/cm3	Boiling Point	430.9±45.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₁₉ClN₄O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	214.4±28.7 °C

Use of PROTO-1

PROTO-1 shows significant protection of hair cells, with HC50(concentration that would produce 50% hair cell survival) of 1 μM-10 μM (1 μM≤HC50≤10 μM).Target:PROTO-1 shows significant protection of hair cells over a broad range of neomycin concentrations, from 25 μM to 400 μM. Pretreatment with 1 and 10 μM PROTO-1 results in significant protection of hair cells exposed to 200 μM neomycin compared to neomycin alone. PROTO-1 protection against neomycin is tested at 4 mM neomycin and showed significant striolar.[2]

Name	PROTO-1
Synonym	More Synonyms

Description	PROTO-1 shows significant protection of hair cells, with HC50(concentration that would produce 50% hair cell survival) of 1 μM-10 μM (1 μM≤HC50≤10 μM).Target:PROTO-1 shows significant protection of hair cells over a broad range of neomycin concentrations, from 25 μM to 400 μM. Pretreatment with 1 and 10 μM PROTO-1 results in significant protection of hair cells exposed to 200 μM neomycin compared to neomycin alone. PROTO-1 protection against neomycin is tested at 4 mM neomycin and showed significant striolar.[2]
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others
References	[1]. Rubel, et al. COMPOUNDS AND METHODS FOR PREVENTING, TREATING AND/OR PROTECTING AGAINST SENSORY HAIR CELL DEATH [2]. Owens KN, et al. Identification of genetic and chemicalm modulators of zebrafish mechanosensory hair cell death. PLoS Genet. 2008 Feb 29;4(2):e1000020.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Others

References

[1]. Rubel, et al. COMPOUNDS AND METHODS FOR PREVENTING, TREATING AND/OR PROTECTING AGAINST SENSORY HAIR CELL DEATH

[2]. Owens KN, et al. Identification of genetic and chemicalm modulators of zebrafish mechanosensory hair cell death. PLoS Genet. 2008 Feb 29;4(2):e1000020.

Density	1.4±0.1 g/cm3
Boiling Point	430.9±45.0 °C at 760 mmHg
Molecular Formula	C₁₇H₁₉ClN₄O₂S
Molecular Weight	378.876
Flash Point	214.4±28.7 °C
Exact Mass	378.091736
LogP	4.30
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.698
Storage condition	2-8℃

Thieno[2,3-c]pyridine-3-carboxamide, 2-[[[(4-chlorophenyl)amino]carbonyl]amino]-6-ethyl-4,5,6,7-tetrahydro-

2-{[(4-Chlorophenyl)carbamoyl]amino}-6-ethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide

MFCD01923572

DC Chemicals Limited
China
Product Name: PROTO-1
Price: $400.0/10mg $1200.0/50mg $1680.0/100mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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Price: $420/5mg

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PROTO-1

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