L(-)-Pipecolinic acid

Modify Date: 2025-08-20 19:06:47

L(-)-Pipecolinic acid Structure
L(-)-Pipecolinic acid structure
 Common Name L(-)-Pipecolinic acid
CAS Number 3105-95-1 Molecular Weight 129.157
Density 1.1±0.1 g/cm3 Boiling Point 265.8±33.0 °C at 760 mmHg
Molecular Formula C6H11NO2 Melting Point 272ºC
MSDS Chinese USA Flash Point 114.5±25.4 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Use of L(-)-Pipecolinic acid


H-HoPro-OH is a breakdown product of lysine, accumulates in body fluids of infants with generalized genetic peroxisomal disorders, such as Zellweger syndrome, neonatal adrenoleukodystrophy.

 Names

Name L-pipecolate
Synonym More Synonyms

 L(-)-Pipecolinic acid Biological Activity

Description H-HoPro-OH is a breakdown product of lysine, accumulates in body fluids of infants with generalized genetic peroxisomal disorders, such as Zellweger syndrome, neonatal adrenoleukodystrophy.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Mihalik SJ, et al. Peroxisomal L-pipecolic acid oxidation is deficient in liver from Zellweger syndrome patients. Pediatr Res. 1989 May;25(5):548-52.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 265.8±33.0 °C at 760 mmHg
Melting Point 272ºC
Molecular Formula C6H11NO2
Molecular Weight 129.157
Flash Point 114.5±25.4 °C
Exact Mass 129.078979
PSA 49.33000
LogP 0.00
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.479
InChIKey HXEACLLIILLPRG-YFKPBYRVSA-N
SMILES O=C(O)C1CCCCN1

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933399090

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles39

More Articles
Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).

Bioorg. Med. Chem. 19 , 6409-18, (2011)

The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitati...

Lysine catabolism in Haemonchus contortus and Teladorsagia circumcincta.

Exp. Parasitol. 131(1) , 101-6, (2012)

Catabolism of lysine through the pipecolate, saccharopine and cadaverine pathways has been investigated in L3 and adult Haemonchus contortus and Teladorsagia circumcincta. Both enzymes of the saccharo...

Characterization of the nocardiopsin biosynthetic gene cluster reveals similarities to and differences from the rapamycin and FK-506 pathways.

ChemBioChem. 16(6) , 990-7, (2015)

Macrolide-pipecolate natural products, such as rapamycin (1) and FK-506 (2), are renowned modulators of FK506-binding proteins (FKBPs). The nocardiopsins, from Nocardiopsis sp. CMB-M0232, are the newe...

 Synonyms

(S)-piperidine-2-carboxylic acid
PIP-OH
L-PIPECOLATE
H-HOMOPRO-OH
(2S)-piperidine-2-carboxylic acid
(S)-2-Piperidinecarboxylic acid
Pipecolinic acid
6-CARBOXYPIPERIDINE
DL-2-Piperidinecarboxylic acid
Pipecolic acid
α-Pipecolinic acid
a-Pipecolinic acid
HOMOPROLINE
L-HOMOPRO
L-Homoproline
(2S)-2-Piperidinecarboxylic acid
h-pip-oh
2-Piperidinecarboxylic acid, (2S)-
H-L-PIP-OH
(S)-Pipecolinic acid
(±)-2-Piperidinecarboxylic acid
2-Piperidinecarboxylic acid
(S)-(−)-2-Piperidinecarboxylic acid L-Homoproline
(L)-Pipecolic acid
(S)-(-)-2-PIPERIDINECARBOXYLIC ACID
L-Pipecolinic acid
EINECS 221-462-1
L-Pipecolic Acid
Pipecolic acid, (S)-(-)-
Dihydrobaikiaine
UNII:H254GW7PVV
(S)-pipecolic acid
L(-)-Pipecolinic acid
DL-Pipecolinicacid
(S)-(−)-2-Piperidinecarboxylic acid
(2S)-piperidinium-2-carboxylate
(±)-Pipecolinic acid
MFCD00005981
2-Piperidinecarboxylic acid, (S)-
(±)-Pipecolic acid
2-Carboxypiperidine
L-pipecolic acid zwitterion
piperidine-2-carboxylic acid
H-HOPRO-OH
L(-)-Pipecolinic acid
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