Zalypsis

Modify Date: 2024-01-10 08:51:20

Zalypsis Structure
Zalypsis structure
Common Name Zalypsis
CAS Number 308359-57-1 Molecular Weight 709.71
Density N/A Boiling Point N/A
Molecular Formula C37H38F3N3O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Zalypsis


Zalypsis (PM00104) has anti-tumor activity. Zalypsis binds to DNA and shows cytotoxicity. Zalypsis inhibits cell cycle and transcription, and leads to double stranded DNA breaks[1][2].

 Names

Name Zalypsis

 Zalypsis Biological Activity

Description Zalypsis (PM00104) has anti-tumor activity. Zalypsis binds to DNA and shows cytotoxicity. Zalypsis inhibits cell cycle and transcription, and leads to double stranded DNA breaks[1][2].
Related Catalog
References

[1]. Duan Z, et al. Diverse cross-resistance phenotype to ET-743 and PM00104 in multi-drug resistant cell lines. Cancer Chemother Pharmacol. 2009 May;63(6):1121-9.  

[2]. Petek BJ, et al. PM00104 (Zalypsis®): a marine derived alkylating agent. Molecules. 2014 Aug 15;19(8):12328-35.  

 Chemical & Physical Properties

Molecular Formula C37H38F3N3O8
Molecular Weight 709.71