NNC 0640

Modify Date: 2025-08-25 16:04:42

NNC 0640 Structure
NNC 0640 structure
Common Name NNC 0640
CAS Number 307986-98-7 Molecular Weight 573.67
Density N/A Boiling Point N/A
Molecular Formula C29H31N7O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NNC 0640


NNC-0640 is a potent human G-protein-coupled glucagon receptor (GCGR) negative allosteric modulator (NAM) with an IC50 of 69.2 nM[1].

 Names

Name NNC-0640

 NNC 0640 Biological Activity

Description NNC-0640 is a potent human G-protein-coupled glucagon receptor (GCGR) negative allosteric modulator (NAM) with an IC50 of 69.2 nM[1].
Related Catalog
Target

Human Glucagon Receptor [1]

References

[1]. Zhang H, et al. Structure of the full-length glucagon class B G-protein-coupled receptor. Nature. 2017 Jun 8;546(7657):259-264.

 Chemical & Physical Properties

Molecular Formula C29H31N7O4S
Molecular Weight 573.67
InChIKey PPTKULJUDJWTSA-UHFFFAOYSA-N
SMILES CS(=O)(=O)c1cccc(NC(=O)N(Cc2ccc(C(=O)Nc3nn[nH]n3)cc2)c2ccc(C3CCCCC3)cc2)c1
Storage condition -20°C
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