307986-98-7

307986-98-7 structure

Name: NNC 0640
Chemical Name: NNC-0640
CAS Number: 307986-98-7
Molecular Formula: C₂₉H₃₁N₇O₄S
Molecular Weight: 573.67
Catalog: Signaling Pathways GPCR/G Protein Glucagon Receptor
Create Date: 2019-06-30 18:03:15
Modify Date: 2025-08-25 16:04:42
NNC-0640 is a potent human G-protein-coupled glucagon receptor (GCGR) negative allosteric modulator (NAM) with an IC50 of 69.2 nM[1].

Name	NNC-0640

Description	NNC-0640 is a potent human G-protein-coupled glucagon receptor (GCGR) negative allosteric modulator (NAM) with an IC50 of 69.2 nM[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Glucagon Receptor
Target	Human Glucagon Receptor [1]
References	[1]. Zhang H, et al. Structure of the full-length glucagon class B G-protein-coupled receptor. Nature. 2017 Jun 8;546(7657):259-264.