GI 181771

Modify Date: 2024-01-09 10:07:36

GI 181771 structure	Common Name	GI 181771
	CAS Number	305366-98-7	Molecular Weight	605.64000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₄H₃₁N₅O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GI 181771

GI 181771 is a cholecystokinin 1 receptor agonist investigated for the treatment of obesity.

Name	3-[[(3S)-2,4-dioxo-1-[2-oxo-2-(N-propan-2-ylanilino)ethyl]-5-phenyl-1,5-benzodiazepin-3-yl]carbamoylamino]benzoic acid
Synonym	More Synonyms

Description	GI 181771 is a cholecystokinin 1 receptor agonist investigated for the treatment of obesity.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Cholecystokinin Receptor Research Areas >> Metabolic Disease
Target	Target: Cholecystokinin 1 receptor[1]
References	[1]. Myer JR, et al. Species- and dose-specific pancreatic responses and progression in single- and repeat-dose studies with GI181771X: a novel cholecystokinin 1 receptor agonist in mice, rats, and monkeys. Toxicol Pathol. 2014 Jan;42(1):260-74. [2]. Roses AD, et al. Stimulation of cholecystokinin-A receptors with Gl181771X: a failed clinical trial that did not test the pharmacogenetic hypothesis for reduction of food intake. Clin Pharmacol Ther. 2009 Apr;85(4):362-5.

Molecular Formula	C₃₄H₃₁N₅O₆
Molecular Weight	605.64000
Exact Mass	605.22700
PSA	142.85000
LogP	5.56250

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GI 181771