Exo2

Modify Date: 2025-08-25 13:06:20

Exo2 Structure
Exo2 structure
Common Name Exo2
CAS Number 304684-77-3 Molecular Weight 354.42600
Density N/A Boiling Point N/A
Molecular Formula C18H18N4O2S Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of Exo2


Exo2 is a secretion inhibitor. Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Exo2 blocks secretory cargo exit from the ER (endoplasmic reticulum) and disrupts the Golgi apparatus, but does not affect the morphology of the TGN (trans-Golgi network) Exo2 can stimulate calcium-dependent exocytosis in permeabilized adrenal chromaff in cells[1][2].

 Names

Name Exo2

 Exo2 Biological Activity

Description Exo2 is a secretion inhibitor. Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Exo2 blocks secretory cargo exit from the ER (endoplasmic reticulum) and disrupts the Golgi apparatus, but does not affect the morphology of the TGN (trans-Golgi network) Exo2 can stimulate calcium-dependent exocytosis in permeabilized adrenal chromaff in cells[1][2].
Related Catalog
References

[1]. Spooner RA, et al. The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Biochem J. 2008 Sep 15;414(3):471-84.

[2]. Morgan A, et al. Exo1 and Exo2 proteins stimulate calcium-dependent exocytosis in permeabilized adrenal chromaffin cells. Nature. 1992 Feb 27;355(6363):833-6.

 Chemical & Physical Properties

Molecular Formula C18H18N4O2S
Molecular Weight 354.42600
Exact Mass 354.11500
PSA 107.87000
LogP 3.80330

 Safety Information

RIDADR NONH for all modes of transport

 Articles1

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