Exo2 structure
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Common Name | Exo2 | ||
|---|---|---|---|---|
| CAS Number | 304684-77-3 | Molecular Weight | 354.42600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H18N4O2S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of Exo2Exo2 is a secretion inhibitor. Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Exo2 blocks secretory cargo exit from the ER (endoplasmic reticulum) and disrupts the Golgi apparatus, but does not affect the morphology of the TGN (trans-Golgi network) Exo2 can stimulate calcium-dependent exocytosis in permeabilized adrenal chromaff in cells[1][2]. |
| Name | Exo2 |
|---|
| Description | Exo2 is a secretion inhibitor. Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Exo2 blocks secretory cargo exit from the ER (endoplasmic reticulum) and disrupts the Golgi apparatus, but does not affect the morphology of the TGN (trans-Golgi network) Exo2 can stimulate calcium-dependent exocytosis in permeabilized adrenal chromaff in cells[1][2]. |
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| Related Catalog | |
| References |
| Molecular Formula | C18H18N4O2S |
|---|---|
| Molecular Weight | 354.42600 |
| Exact Mass | 354.11500 |
| PSA | 107.87000 |
| LogP | 3.80330 |
| RIDADR | NONH for all modes of transport |
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The perilipin-2 (adipophilin) coat of cytosolic lipid droplets is regulated by an Arf1-dependent mechanism in HC11 mouse mammary epithelial cells.
Cell Biol. Int. 40 , 143-55, (2016) The cytosolic lipid droplets (cLDs) store excess intracellular lipids, and perilipin-2 is believed to protect cLDs from degradation. Here, we investigated the role of the small G-protein Arf1 and the ... |