DFPM

Modify Date: 2025-08-26 11:07:01

DFPM Structure
DFPM structure
Common Name DFPM
CAS Number 301338-95-4 Molecular Weight 340.267
Density 1.3±0.1 g/cm3 Boiling Point 461.2±55.0 °C at 760 mmHg
Molecular Formula C16H15Cl2NOS Melting Point N/A
MSDS N/A Flash Point 232.7±31.5 °C

 Use of DFPM


A small molecule that rapidly downregulates abscisic acid (ABA)-dependent gene expression (IC50=3 and 1.5 uM for RD29B and RAB18 promoters), also inhibits ABA-induced stomatal closure; stimulates expression of plant defense-related genes, major early regulators of pathogen-resistance responses, including EDS1, PAD4, RAR1, and SGT1b, are required for DFPM-interference with ABA signal transduction, disrupts cytosolic Ca(2+) signaling and downstream anion channel activation in a PAD4-dependent manner.

 Names

Name [5-(3,4-Dichlorophenyl)-2-furyl](1-piperidinyl)methanethione
Synonym More Synonyms

 DFPM Biological Activity

Description A small molecule that rapidly downregulates abscisic acid (ABA)-dependent gene expression (IC50=3 and 1.5 uM for RD29B and RAB18 promoters), also inhibits ABA-induced stomatal closure; stimulates expression of plant defense-related genes, major early regulators of pathogen-resistance responses, including EDS1, PAD4, RAR1, and SGT1b, are required for DFPM-interference with ABA signal transduction, disrupts cytosolic Ca(2+) signaling and downstream anion channel activation in a PAD4-dependent manner.
References References 1. Kim TH, et al. Curr Biol. 2011 Jun 7;21(11):990-7. View Related Products by Target Other Targets

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 461.2±55.0 °C at 760 mmHg
Molecular Formula C16H15Cl2NOS
Molecular Weight 340.267
Flash Point 232.7±31.5 °C
Exact Mass 339.025146
LogP 3.95
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.627

 Synonyms

[5-(3,4-Dichlorophenyl)-2-furyl](1-piperidinyl)methanethione
[5-(3,4-Dichlorophenyl)-2-furyl](piperidin-1-yl)methanethione
MFCD02213714
Methanethione, [5-(3,4-dichlorophenyl)-2-furanyl]-1-piperidinyl-
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