DFPM

Names

[ Name ]:
DFPM

[Synonym ]:
[5-(3,4-Dichlorophenyl)-2-furyl](1-piperidinyl)methanethione
[5-(3,4-Dichlorophenyl)-2-furyl](piperidin-1-yl)methanethione
MFCD02213714
Methanethione, [5-(3,4-dichlorophenyl)-2-furanyl]-1-piperidinyl-

Biological Activity

[Description]:

A small molecule that rapidly downregulates abscisic acid (ABA)-dependent gene expression (IC50=3 and 1.5 uM for RD29B and RAB18 promoters), also inhibits ABA-induced stomatal closure; stimulates expression of plant defense-related genes, major early regulators of pathogen-resistance responses, including EDS1, PAD4, RAR1, and SGT1b, are required for DFPM-interference with ABA signal transduction, disrupts cytosolic Ca(2+) signaling and downstream anion channel activation in a PAD4-dependent manner.

[References]

References 1. Kim TH, et al. Curr Biol. 2011 Jun 7;21(11):990-7. View Related Products by Target Other Targets

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
461.2±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₆H₁₅Cl₂NOS

[ Molecular Weight ]:
340.267

[ Flash Point ]:
232.7±31.5 °C

[ Exact Mass ]:
339.025146

[ LogP ]:
3.95

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.627

Related Compounds

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