301338-95-4

301338-95-4 structure

Name: DFPM
Chemical Name: [5-(3,4-Dichlorophenyl)-2-furyl](1-piperidinyl)methanethione
CAS Number: 301338-95-4
Molecular Formula: C₁₆H₁₅Cl₂NOS
Molecular Weight: 340.267
Catalog: Research Areas Others
Create Date: 2020-01-11 22:04:58
Modify Date: 2025-08-26 11:07:01
A small molecule that rapidly downregulates abscisic acid (ABA)-dependent gene expression (IC50=3 and 1.5 uM for RD29B and RAB18 promoters), also inhibits ABA-induced stomatal closure; stimulates expression of plant defense-related genes, major early regulators of pathogen-resistance responses, including EDS1, PAD4, RAR1, and SGT1b, are required for DFPM-interference with ABA signal transduction, disrupts cytosolic Ca(2+) signaling and downstream anion channel activation in a PAD4-dependent manner.

Name	[5-(3,4-Dichlorophenyl)-2-furyl](1-piperidinyl)methanethione
Synonyms	[5-(3,4-Dichlorophenyl)-2-furyl](1-piperidinyl)methanethione [5-(3,4-Dichlorophenyl)-2-furyl](piperidin-1-yl)methanethione MFCD02213714 Methanethione, [5-(3,4-dichlorophenyl)-2-furanyl]-1-piperidinyl-

Description	A small molecule that rapidly downregulates abscisic acid (ABA)-dependent gene expression (IC50=3 and 1.5 uM for RD29B and RAB18 promoters), also inhibits ABA-induced stomatal closure; stimulates expression of plant defense-related genes, major early regulators of pathogen-resistance responses, including EDS1, PAD4, RAR1, and SGT1b, are required for DFPM-interference with ABA signal transduction, disrupts cytosolic Ca(2+) signaling and downstream anion channel activation in a PAD4-dependent manner.
References	References 1. Kim TH, et al. Curr Biol. 2011 Jun 7;21(11):990-7. View Related Products by Target Other Targets