N-Carbethoxy-4-piperidone
Modify Date: 2024-01-02 20:24:40
N-Carbethoxy-4-piperidone structure
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Common Name | N-Carbethoxy-4-piperidone | ||
|---|---|---|---|---|
| CAS Number | 29976-53-2 | Molecular Weight | 171.194 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 273.4±33.0 °C at 760 mmHg | |
| Molecular Formula | C8H13NO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 87.8±0.0 °C | |
Use of N-Carbethoxy-4-piperidoneN-Carbethoxy-4-piperidone is a metabolite of Loratadine (HY-17043). Loratadine is a selective inverse peripheral histamine H1-receptor agonist, and shows anti-dengue-virus (DENV) activity[1][2][3]. |
| Name | N-Carbethoxy-4-piperidone |
|---|---|
| Synonym | More Synonyms |
| Description | N-Carbethoxy-4-piperidone is a metabolite of Loratadine (HY-17043). Loratadine is a selective inverse peripheral histamine H1-receptor agonist, and shows anti-dengue-virus (DENV) activity[1][2][3]. |
|---|---|
| In Vitro | N-Carbethoxy-4-piperidone (piperidinone 4) shows toxicity to C. dubia, B. calyciflorus and P. subcapitata[1]. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 273.4±33.0 °C at 760 mmHg |
| Molecular Formula | C8H13NO3 |
| Molecular Weight | 171.194 |
| Flash Point | 87.8±0.0 °C |
| Exact Mass | 171.089539 |
| PSA | 46.61000 |
| LogP | -0.31 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.483 |
| Storage condition | 2-8°C |
| Water Solubility | slightly soluble |
| Hazard Codes | Xn:Harmful |
|---|---|
| Risk Phrases | R22;R36/38 |
| Safety Phrases | S23-S24/25-S37/39-S26 |
| WGK Germany | 3 |
| HS Code | 2933399090 |
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~98%
N-Carbethoxy-4-... CAS#:29976-53-2 |
| Literature: SUVEN LIFE SCIENCES LIMITED; Nirogi, Ramakrishna; Mohammed, Abdul Rasheed; Yarlagadda, Suresh; Ravella, Srinivasa Rao; Shinde, Anil Karbhari; Kamphampati, Ramasastri; Roayapalley, Praveen Kumar; Jayarajan, Pradeep; Bhyrapuneni, Gopinadh; Patnala, Sriramachandra Murthy; Ravula, Jyothsna; Jasti, Venkateswarlu Patent: US2014/187581 A1, 2014 ; Location in patent: Paragraph 0195-0198 ; |
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~%
N-Carbethoxy-4-... CAS#:29976-53-2 |
| Literature: US2005/234046 A1, ; Page/Page column 59 ; US 20050234046 A1 |
|
~%
N-Carbethoxy-4-... CAS#:29976-53-2 |
| Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 20 p. 5439 - 5442 |
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~%
N-Carbethoxy-4-... CAS#:29976-53-2 |
| Literature: Tetrahedron Letters, , vol. 34, # 24 p. 3863 - 3866 |
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~73%
N-Carbethoxy-4-... CAS#:29976-53-2 |
| Literature: Praliev, K. D.; Belikova, N. A.; Isin, Zh. I.; Sokolov, D. V. Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 1 p. 60 - 61 Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 1 p. 70 - 71 |
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~%
N-Carbethoxy-4-... CAS#:29976-53-2 |
| Literature: Tetrahedron Letters, , vol. 34, # 24 p. 3863 - 3866 |
![ethyl 1,4-dioxa-8-azaspiro[4.5]decane-8-carboxylate structure](https://www.chemsrc.com/caspic/406/51787-77-0.png)
| Precursor 7 | |
|---|---|
| DownStream 10 | |
![ETHYL 8-FLUORO-1,3,4,5-TETRAHYDRO-2H-PYRIDO[4,3-B]INDOLE-2-CARBOXYLATE structure](https://www.chemsrc.com/caspic/393/58038-66-7.png)
CAS#:58038-66-7
CAS#:50706-57-5
CAS#:40807-61-2![3H-Spiro[2-benzofuran-1,4'-piperidine] structure](https://www.chemsrc.com/caspic/450/38309-60-3.png)
CAS#:38309-60-3
CAS#:5382-16-1![ETHYL 3H-SPIRO[ISOBENZOFURAN-1,4'-PIPERIDINE]-1'-CARBOXYLATE structure](https://www.chemsrc.com/caspic/255/42191-83-3.png)
CAS#:42191-83-3
CAS#:50492-22-3
CAS#:3888-65-1![Spiro[isochroman-1,4'-piperidine] structure](https://www.chemsrc.com/caspic/232/180160-97-8.png)
CAS#:180160-97-8
CAS#:19786-58-4| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Ethyl 4-oxo-1-piperidinecarboxylate |
| N-carboethoxy-4-piperidinone |
| 1-CARBETHOXY-4-PIPERIDONE |
| 4-oxo-piperidine-1-carboxylic acid ethyl ester |
| EINECS 249-984-5 |
| AURORA KA-3057 |
| MFCD00006188 |
| N-Ethoxycarbonyl-4-piperidinone |
| 1-Ethoxycarbonyl-4-piperidinone |
| ethyl 4-oxopiperidine-1-carboxylate |
| N-ETHOXYCARBONYL-4-PIPERIDONE |
| N-Carbethoxy-4-piperidone |
| 1-Carbethoxy-4-piperidone,1-Ethoxycarbonyl-4-piperidone,Ethyl 4-oxo-1-piperidinecarboxylate |
| 1-(Ethoxycarbonyl)-4-piperidone |
| carbethoxy-4-piperidone |
| 4-Oxo-1-piperidinecarboxylic acid ethyl ester |
| N-Carbethoxy-4-piperidon |
| Ethyl-4-oxopiperidin-1-carboxylat |
| 1-carboethoxy-4-piperidone |
| 1-Ethoxycarbonyl-4-oxopiperidine |
| Loratadine impurity H |
| N-CARBOETHOXY-4-PIPERIDONE |
| 1-Piperidinecarboxylic acid, 4-oxo-, ethyl ester |
| 1-Ethoxycarbonyl-4-piperidone |
| N-Carbithoxy-4-Piperidone |
| N-Carbethoxypiperidone |
| Loratadine Impurity 8 |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: N-Carbethoxy-4-piperidone
- Price: ￥108.0/25g ￥308.0/100g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: N-Carbethoxy-4-piperidone
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Ethyl 4-oxo-1-piperidinecarboxylate
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
- Xi'an Reach Pharmaceutical Technology Co.,Ltd.
- China
- Product Name: N-Carbethoxy-4-Piperidone
- Price: ￥Inquiry/1kg
- Purity: 96.0%
- Stocking Period: Inquiry
- Contact: Grace
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: N-Carbethoxy-4-piperidone
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
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