RPL-554

Modify Date: 2025-08-25 11:46:27

RPL-554 Structure
RPL-554 structure
Common Name RPL-554
CAS Number 298680-25-8 Molecular Weight 477.56
Density N/A Boiling Point N/A
Molecular Formula C26H31N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RPL-554


(E/Z)-Ensifentrine is a dual inhibitor of PDE3/4. (E/Z)-Ensifentrine reduces the inflammatory cells into the airways. (E/Z)-Ensifentrine has bronchodilatory and anti-inflammatory activities in vitro and in vivo model[1].

 Names

Name 2-[9,10-dimethoxy-4-oxo-2-(2,4,6-trimethylphenyl)imino-6,7-dihydropyrimido[6,1-a]isoquinolin-3-yl]ethylurea
Synonym More Synonyms

 RPL-554 Biological Activity

Description (E/Z)-Ensifentrine is a dual inhibitor of PDE3/4. (E/Z)-Ensifentrine reduces the inflammatory cells into the airways. (E/Z)-Ensifentrine has bronchodilatory and anti-inflammatory activities in vitro and in vivo model[1].
Related Catalog
References

[1]. Page CP, et al. Phosphodiesterase inhibitors for the treatment of asthma and chronic obstructive pulmonary disease. Int Arch Allergy Immunol. 2014;165(3):152-64.  

 Chemical & Physical Properties

Molecular Formula C26H31N5O4
Molecular Weight 477.56
Exact Mass 477.23800
PSA 113.86000
LogP 3.62070

 Synonyms

unii-3e3d8t1gix
rpl-554
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