VEGFR-2-IN-37

Modify Date: 2025-12-01 00:31:13

VEGFR-2-IN-37 Structure
VEGFR-2-IN-37 structure
Common Name VEGFR-2-IN-37
CAS Number 298207-77-9 Molecular Weight 324.40
Density N/A Boiling Point N/A
Molecular Formula C18H16N2O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of VEGFR-2-IN-37


VEGFR-2-IN-37 (compound 12) is an inhibitor of VEGFR-2. The inhibition rate at 200 μM was approximately 56.9 μM. VEGFR-2-IN-37 is a potential inhibitor of human umbilical vein endothelial cell (HUVEC) proliferation[1].

 Names

Name WAY-357919
Synonym More Synonyms

 VEGFR-2-IN-37 Biological Activity

Description VEGFR-2-IN-37 (compound 12) is an inhibitor of VEGFR-2. The inhibition rate at 200 μM was approximately 56.9 μM. VEGFR-2-IN-37 is a potential inhibitor of human umbilical vein endothelial cell (HUVEC) proliferation[1].
Related Catalog
Target

VEGFR-2[1]

References

[1]. Perspicace E, et al. Design, synthesis and biological evaluation of new classes of thieno[3,2-d]pyrimidinone and thieno[1,2,3]triazine as inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2). Eur J Med Chem. 2013 May;63:765-81.  

 Chemical & Physical Properties

Molecular Formula C18H16N2O2S
Molecular Weight 324.40
InChIKey STAQHFQLHGDVFW-UHFFFAOYSA-N
SMILES CC(=O)c1cccc(Oc2ncnc3sc4c(c23)CCCC4)c1

 Synonyms

3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenone
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