298207-77-9

298207-77-9 structure

Name: VEGFR-2-IN-37
Chemical Name: WAY-357919
CAS Number: 298207-77-9
Molecular Formula: C₁₈H₁₆N₂O₂S
Molecular Weight: 324.40
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK VEGFR
Create Date: 2023-01-19 15:46:12
Modify Date: 2024-04-06 07:18:16
VEGFR-2-IN-37 (compound 12) is an inhibitor of VEGFR-2. The inhibition rate at 200 μM was approximately 56.9 μM. VEGFR-2-IN-37 is a potential inhibitor of human umbilical vein endothelial cell (HUVEC) proliferation[1].

Name	WAY-357919
Synonyms	3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenone

Description	VEGFR-2-IN-37 (compound 12) is an inhibitor of VEGFR-2. The inhibition rate at 200 μM was approximately 56.9 μM. VEGFR-2-IN-37 is a potential inhibitor of human umbilical vein endothelial cell (HUVEC) proliferation[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	VEGFR-2[1]
References	[1]. Perspicace E, et al. Design, synthesis and biological evaluation of new classes of thieno[3,2-d]pyrimidinone and thieno[1,2,3]triazine as inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2). Eur J Med Chem. 2013 May;63:765-81.

Molecular Formula	C₁₈H₁₆N₂O₂S
Molecular Weight	324.40