selenocystine

Modify Date: 2024-01-02 23:42:27

selenocystine structure	Common Name	selenocystine
	CAS Number	29621-88-3	Molecular Weight	334.091
	Density	N/A	Boiling Point	538.3±60.0 °C at 760 mmHg
	Molecular Formula	C₆H₁₂N₂O₄Se₂	Melting Point	224.5-229.5ºC(lit.)
	MSDS	Chinese USA	Flash Point	279.3±32.9 °C
	Symbol	GHS06, GHS08, GHS09	Signal Word	Danger

Use of selenocystine

L-Selenocystine is a diselenide-bridged amino acid. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types[1].

Name	(2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]diselanyl]propanoic acid
Synonym	More Synonyms

Description	L-Selenocystine is a diselenide-bridged amino acid. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Michio Iwaoka, et al. Synthesis of selenocysteine and selenomethionine derivatives from sulfur-containing amino acids. Chem Biodivers. 2008 Mar;5(3):359-74.Michio Iwaoka, et al. Synthesis of selenocysteine and selenomethionine derivatives from sulfur-containing amino acids. Chem Biodivers. 2008 Mar;5(3):359-74.

Boiling Point	538.3±60.0 °C at 760 mmHg
Melting Point	224.5-229.5ºC(lit.)
Molecular Formula	C₆H₁₂N₂O₄Se₂
Molecular Weight	334.091
Flash Point	279.3±32.9 °C
Exact Mass	335.912750
PSA	126.64000
LogP	1.86
Appearance of Characters	Powder \| Yellow
Vapour Pressure	0.0±3.1 mmHg at 25°C
Storage condition	2-8°C

selenocystine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY6032000

CHEMICAL NAME :: Alanine, 3,3'-diselenodi-, L-

CAS REGISTRY NUMBER :: 29621-88-3

LAST UPDATED :: 199712

DATA ITEMS CITED :: 18

MOLECULAR FORMULA :: C6-H12-N2-O4-Se2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8463 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 108,437,1953 *** REVIEWS *** ACGIH TLV-TWA 0.2 mg(Se)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-AUSTRALIA:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-BELGIUM:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-DENMARK:TWA 0.1 mg(Se)/m3 JAN 1993 OEL-FINLAND:TWA 0.1 mg(Se)/m3;STEL 0.3 mg(Se)/m3 JAN 1993 OEL-GERMANY:TWA 0.1 mg(Se)/m3 JAN 1993 OEL-HUNGARY:STEL 0.1 mg(Se)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-POLAND:TWA 0.1 mg(Se)/m3 JAN 1993 OEL-SWEDEN:TWA 0.1 mg(Se)/m3 JAN 1993 OEL-SWITZERLAND:TWA 0.1 mg(Se)/m3 JAN 1993 OEL-TURKEY:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 mg(Se)/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

Symbol	GHS06, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H301 + H331-H373-H410
Precautionary Statements	P261-P273-P301 + P310-P311-P501
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T: Toxic;N: Dangerous for the environment;
Risk Phrases	R23/25
Safety Phrases	S28;S45;S60;S61
RIDADR	UN 3283 6.1/PG 3
WGK Germany	3
RTECS	AY6032000
Packaging Group	III
HS Code	2930909090

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Determination of selenium and its compounds in marine organisms.

J. Trace Elem. Med. Biol. 29 , 91-8, (2015)

In this study, we investigate the type and quantity of selenium compounds in fish and marine organisms, using ion-pair reversed phase LC–ICP-MS, developed and applied for the analysis of Atlantic cod,...

Effects of selenium on development, survival, and accumulation in the honeybee (Apis mellifera L.).

Environ. Toxicol. Chem. 32(11) , 2584-92, (2013)

Apis mellifera L. (Hymenoptera: Apidae) is an important agricultural pollinator in the United States and throughout the world. In areas of selenium (Se) contamination, honeybees may be at risk because...

Selenocystine induces reactive oxygen species–mediated apoptosis in human cancer cells

Biomed. Pharmacother. 63(2) , 105-13, (2009)

Epidemiological and clinical studies have demonstrated that dietary supplementation of selenium (Se) could reduce the incidence of human cancers. In this study, selenocystine, a nutritionally availabl...

selenocystine,(L)-isomer

selenocystine

L-Selenocystine

C6H12N2O4Se2

L-3,3'-Diselenodialanine

Seleno-L-cystine Monohydrate

seleno-DL-cystine

UNII:493154PTZ7

(l,l)-selenocystine

(2R,2'R)-3,3'-Diselane-1,2-diylbis(2-aminopropanoic acid) (non-preferred name)

(R,R)-3,3'-Diselenobis(2-aminopropionic Acid) Monohydrate

L-Alanine,3,3'-diselenobis

(2R,2'R)-3,3'-(1,2-Diselanediyl)bis(2-aminopropanoic acid)

Seleno-L-cystine

Alanine,3,3'-diselenodi-,L

MFCD00800971

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: selenocystine
Price: ￥1428.0/200mg ￥548.0/50mg ￥398.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: L-Selenocystine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Zhejiang Hangyu API Co., Ltd
China
Product Name: L-SELENOCYSTINE
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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