DprE1-IN-9

Modify Date: 2024-10-01 15:13:23

DprE1-IN-9 structure	Common Name	DprE1-IN-9
	CAS Number	2906099-98-5	Molecular Weight	434.45
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₅F₃N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DprE1-IN-9

DprE1-IN-9 (compound B18) is an effective reversible DprE1 inhibitor and can bind to the receptor cavity of DprE1. DprE1-IN-9 shows strong antimycobacterial activity not only against non-pathogenic strain H37Ra (MIC=0.18 µg/mL) but also against pathogenic H37Rv and the clinical MDR and XDR isolates[1].

Name	DprE1-IN-9

Description	DprE1-IN-9 (compound B18) is an effective reversible DprE1 inhibitor and can bind to the receptor cavity of DprE1. DprE1-IN-9 shows strong antimycobacterial activity not only against non-pathogenic strain H37Ra (MIC=0.18 µg/mL) but also against pathogenic H37Rv and the clinical MDR and XDR isolates[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Wang Xiang, et al. Discovery of novel reversible inhibitor of DprE1 based on benzomorpholine for the treatment of tuberculosis. Microbiol Spectr. 2023 Sep 12:e0472122.

Molecular Formula	C₂₂H₂₅F₃N₄O₂
Molecular Weight	434.45

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DprE1-IN-9

Use of DprE1-IN-9

Names

DprE1-IN-9 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.