LSD1-IN-27

Modify Date: 2024-04-09 18:10:31

LSD1-IN-27 structure	Common Name	LSD1-IN-27
	CAS Number	2904571-94-2	Molecular Weight	355.48
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₅N₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of LSD1-IN-27

LSD1-IN-27 (Compound 5ac) is a LSD1 inhibitor (IC50: 13 nM). LSD1-IN-27 inhibits the stemness and migration of gastric cancer cells. LSD1-IN-27 also reduces the expression of PD-L1 in BGC-823 and MFC cells. LSD1-IN-27 can enhance T cell immune response in gastric cancer[1].

Name	LSD1-IN-27

Description	LSD1-IN-27 (Compound 5ac) is a LSD1 inhibitor (IC50: 13 nM). LSD1-IN-27 inhibits the stemness and migration of gastric cancer cells. LSD1-IN-27 also reduces the expression of PD-L1 in BGC-823 and MFC cells. LSD1-IN-27 can enhance T cell immune response in gastric cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Demethylase Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1
Target	13 nM (LSD1)[1]
References	[1]. Dai XJ, et al. Novel acridine-based LSD1 inhibitors enhance immune response in gastric cancer. Eur J Med Chem. 2023 Nov 5;259:115684.

Molecular Formula	C₂₄H₂₅N₃
Molecular Weight	355.48
InChIKey	COFJGRODNLNWAE-UHFFFAOYSA-N
SMILES	Cc1ccc2nc3c(C)c(C)ccc3c(Nc3ccc(N(C)C)cc3)c2c1

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: LSD1-IN-27
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Purity: 98.65%
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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.