2904571-94-2

2904571-94-2 structure

Name: LSD1-IN-27
Chemical Name: LSD1-IN-27
CAS Number: 2904571-94-2
Molecular Formula: C₂₄H₂₅N₃
Molecular Weight: 355.48
Catalog: Signaling Pathways Epigenetics Histone Demethylase
Create Date: 2024-04-09 18:10:31
Modify Date: 2024-04-09 18:10:31
LSD1-IN-27 (Compound 5ac) is a LSD1 inhibitor (IC50: 13 nM). LSD1-IN-27 inhibits the stemness and migration of gastric cancer cells. LSD1-IN-27 also reduces the expression of PD-L1 in BGC-823 and MFC cells. LSD1-IN-27 can enhance T cell immune response in gastric cancer[1].

Name	LSD1-IN-27

Description	LSD1-IN-27 (Compound 5ac) is a LSD1 inhibitor (IC50: 13 nM). LSD1-IN-27 inhibits the stemness and migration of gastric cancer cells. LSD1-IN-27 also reduces the expression of PD-L1 in BGC-823 and MFC cells. LSD1-IN-27 can enhance T cell immune response in gastric cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Demethylase Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1
Target	13 nM (LSD1)[1]
References	[1]. Dai XJ, et al. Novel acridine-based LSD1 inhibitors enhance immune response in gastric cancer. Eur J Med Chem. 2023 Nov 5;259:115684.

Molecular Formula	C₂₄H₂₅N₃
Molecular Weight	355.48