Antifungal agent 52

Modify Date: 2024-02-13 06:16:42

Antifungal agent 52 Structure
Antifungal agent 52 structure
Common Name Antifungal agent 52
CAS Number 2901064-06-8 Molecular Weight 553.81
Density N/A Boiling Point N/A
Molecular Formula C25H19BrClFN6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antifungal agent 52


Antifungal agent 52 (compound 6c) is a tetrazole derivative. Antifungal agent 52 inhibits the synthesis of Ergosterol (HY-N0181). Antifungal agent 52 exhibit a significant antifungal activity against Candida albicans. Antifungal agent 52 affects C. albicans sessile cell membrane permeabilization[1].

 Names

Name Antifungal agent 52

 Antifungal agent 52 Biological Activity

Description Antifungal agent 52 (compound 6c) is a tetrazole derivative. Antifungal agent 52 inhibits the synthesis of Ergosterol (HY-N0181). Antifungal agent 52 exhibit a significant antifungal activity against Candida albicans. Antifungal agent 52 affects C. albicans sessile cell membrane permeabilization[1].
Related Catalog
In Vitro Antifungal agent 52 (compound 6c) (16 μg/mL, 18 h) 处理的细胞进入G0/G1期(代谢状态/细胞增殖)以维持子细胞[1]。 Antifungal agent 52 在 >64 μg/mL 时显示出显着毒性,并且对口腔癌细胞系 TR146 没有毒性[1]。
References

[1]. Staniszewska M, et al. Tetrazole derivatives bearing benzodiazepine moiety-synthesis and action mode against virulence of Candida albicans. Eur J Med Chem. 2022 Feb 15;230:114060.  

 Chemical & Physical Properties

Molecular Formula C25H19BrClFN6O
Molecular Weight 553.81
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