Pectolinarin

Modify Date: 2024-01-02 19:55:49

Pectolinarin Structure
Pectolinarin structure
 Common Name Pectolinarin
CAS Number 28978-02-1 Molecular Weight 622.571
Density 1.6±0.1 g/cm3 Boiling Point 896.4±65.0 °C at 760 mmHg
Molecular Formula C29H34O15 Melting Point N/A
MSDS Chinese USA Flash Point 292.4±27.8 °C

 Use of Pectolinarin


Pectolinarin, isolated from Cirsium chanroenicum, possesses anti-inflammatory activity[1]. Pectolinarin inhibits secretion of IL-6 and IL-8, as well as the production of PGE2 and NO. Pectolinarin suppresses cell proliferation and inflammatory response and induces apoptosis via inactivation of the PI3K/Akt pathway[2].

 Names

Name Pectolinarin
Synonym More Synonyms

 Pectolinarin Biological Activity

Description Pectolinarin, isolated from Cirsium chanroenicum, possesses anti-inflammatory activity[1]. Pectolinarin inhibits secretion of IL-6 and IL-8, as well as the production of PGE2 and NO. Pectolinarin suppresses cell proliferation and inflammatory response and induces apoptosis via inactivation of the PI3K/Akt pathway[2].
Related Catalog
Target

IL-6

IL-8

PGE2

NO

Apoptosis
In Vitro Pectolinarin increases Bax level, and decreases Bcl-2 level in rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs). Pectolinarin inactivates the PI3K/Akt pathway in RA-FLSs[2].
References

[1]. Lim H, et al. Anti-inflammatory activity of pectolinarigenin and pectolinarin isolated from Cirsium chanroenicum. Biol Pharm Bull. 2008 Nov;31(11):2063-7.

[2]. Wang L, et al. Pectolinarin inhibits proliferation, induces apoptosis, and suppresses inflammation in rheumatoid arthritis fibroblast-like synoviocytes by inactivating the phosphatidylinositol 3 kinase/protein kinase B pathway.J Cell Biochem. 2019 Sep;120(9):15202-15210.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 896.4±65.0 °C at 760 mmHg
Molecular Formula C29H34O15
Molecular Weight 622.571
Flash Point 292.4±27.8 °C
Exact Mass 622.189758
PSA 227.20000
LogP 1.71
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.683
Storage condition 2~8℃

 Safety Information

Hazard Codes Xi
RIDADR NONH for all modes of transport
HS Code 29389090

 Synthetic Route

acetone oxime hydrochloride structure

acetone oxime h...

CAS#:4154-21-6

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Pectolinarin Structure

Pectolinarin

CAS#:28978-02-1
Literature: Zemplen; Bognar Chemische Berichte, 1941 , vol. 74, p. 1818,1821

 Precursor & DownStream

Precursor  1

DownStream  1

 Synonyms

5-Hydroxy-6-methoxy-2-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
5-hydroxy-6-methoxy-2-(4-methoxyphenyl)
5-Hydroxy-6-methoxy-2-(4-methoxyphenyl)-7-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
neolinarin
Pectolinaroside
4H-1-Benzopyran-4-one, 7-((6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl)oxy)-5-hydroxy-6-methoxy-2-(4-methoxyphenyl)-
Pectolinarigenin 7-Rutinoside
PECTOLINARIN(P)
7-((6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl)oxy)-5-hydroxy-6-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
Pectolinarin
4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-6-methoxy-2-(4-methoxyphenyl)-
pectolinarigenin 7-O-rutinoside
Top Suppliers:I want be here
  • BioBioPha
  • China
  • Product Name: Pectolinarin
  • Price: ￥Inquiry/5mg
  • Purity: 98.0%
  • Stocking Period: 1 Day
  • Contact: Xueping-Zheng

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Price: ￥500/5 mg

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Related Compounds: More...
Pectolinarin
134-33-8
Chemsrc provides Pectolinarin(CAS#:28978-02-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Pectolinarin are included as well.>> amp version: Pectolinarin

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