Antifungal agent 51
Modify Date: 2025-09-17 17:24:22
Antifungal agent 51 structure
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Common Name | Antifungal agent 51 | ||
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| CAS Number | 2896209-47-3 | Molecular Weight | 369.42 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H16FN5OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Antifungal agent 51Antifungal agent 51 (5c) has potent antifungal activity, especially against Candida albicans FDC 151 , Candida parapsilosis ATCC 22019 and Candida tropicalis FDC 138, with the MIC value is less than 0.063 μg/mL, and it has low toxicity to cells and no carcinogenicity[1]. |
| Name | Antifungal agent 51 |
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| Description | Antifungal agent 51 (5c) has potent antifungal activity, especially against Candida albicans FDC 151 , Candida parapsilosis ATCC 22019 and Candida tropicalis FDC 138, with the MIC value is less than 0.063 μg/mL, and it has low toxicity to cells and no carcinogenicity[1]. |
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| Related Catalog | |
| In Vitro | Antifungal agent 51 具有很强的抗真菌活性，尤其是对白色念珠菌 FDC 151、近平滑念珠菌 ATCC 22019 和热带念珠菌 FDC 138，具有 MIC 值 小于 0.063 μg/mL，对白色念珠菌 CMRC 19 和光滑念珠菌FDC 192，MIC 值为 0.125 μg/mL，对白色念珠菌 CMRC 192，MIC 值为 0.25 μg/mL，对抗光滑念珠菌 CMRC 89，MIC 值为 1 μg/mL[1]。 Antifungal agent 51（6.25、12.5、25 μg/mL；48 小时）在 BEAS-2B 和 HepG2 细胞中即使在 25 μg/mL 的相对高浓度下也会部分影响细胞系的活力[1]。 Cell Viability Assay[1] Cell Line: BEAS-2B and HepG2 cells Concentration: 6.25, 12.5, and 25 μg/mL Incubation Time: 48 h Result: Partially affected the viability of cell lines even at relatively high concentration of 25 μg/mL in BEAS-2B and HepG2 cells |
| References |
| Molecular Formula | C18H16FN5OS |
|---|---|
| Molecular Weight | 369.42 |
| InChIKey | LUOGHIFDYWBLNG-UHFFFAOYSA-N |
| SMILES | OC(CSc1nc2ccccc2[nH]1)(Cn1cncn1)c1ccc(F)cc1 |