2896209-47-3
2896209-47-3 structure
- Name: Antifungal agent 51
- Chemical Name: Antifungal agent 51
- CAS Number: 2896209-47-3
- Molecular Formula: C18H16FN5OS
- Molecular Weight: 369.42
- Catalog: Signaling Pathways Anti-infection Fungal
- Create Date: 2023-08-11 14:10:33
- Modify Date: 2024-09-23 13:17:29
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Antifungal agent 51 (5c) has potent antifungal activity, especially against Candida albicans FDC 151 , Candida parapsilosis ATCC 22019 and Candida tropicalis FDC 138, with the MIC value is less than 0.063 μg/mL, and it has low toxicity to cells and no carcinogenicity[1].
| Name | Antifungal agent 51 |
|---|
| Description | Antifungal agent 51 (5c) has potent antifungal activity, especially against Candida albicans FDC 151 , Candida parapsilosis ATCC 22019 and Candida tropicalis FDC 138, with the MIC value is less than 0.063 μg/mL, and it has low toxicity to cells and no carcinogenicity[1]. |
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| Related Catalog | |
| In Vitro | Antifungal agent 51 具有很强的抗真菌活性，尤其是对白色念珠菌 FDC 151、近平滑念珠菌 ATCC 22019 和热带念珠菌 FDC 138，具有 MIC 值 小于 0.063 μg/mL，对白色念珠菌 CMRC 19 和光滑念珠菌FDC 192，MIC 值为 0.125 μg/mL，对白色念珠菌 CMRC 192，MIC 值为 0.25 μg/mL，对抗光滑念珠菌 CMRC 89，MIC 值为 1 μg/mL[1]。 Antifungal agent 51（6.25、12.5、25 μg/mL；48 小时）在 BEAS-2B 和 HepG2 细胞中即使在 25 μg/mL 的相对高浓度下也会部分影响细胞系的活力[1]。 Cell Viability Assay[1] Cell Line: BEAS-2B and HepG2 cells Concentration: 6.25, 12.5, and 25 μg/mL Incubation Time: 48 h Result: Partially affected the viability of cell lines even at relatively high concentration of 25 μg/mL in BEAS-2B and HepG2 cells |
| References |
| Molecular Formula | C18H16FN5OS |
|---|---|
| Molecular Weight | 369.42 |