pan-KRAS-IN-4

Modify Date: 2025-09-18 11:56:28

pan-KRAS-IN-4 Structure
pan-KRAS-IN-4 structure
 Common Name pan-KRAS-IN-4
CAS Number 2885961-55-5 Molecular Weight 636.69
Density N/A Boiling Point N/A
Molecular Formula C36H34F2N6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of pan-KRAS-IN-4


pan-KRAS-IN-4 (compound 5) is a potent inhibitor of KRAS with IC50s of 0.37 nM (Kras G12C), 0.19 nM (Kras G12V), respectively[1].

 Names

Name pan-KRAS-IN-4

 pan-KRAS-IN-4 Biological Activity

Description pan-KRAS-IN-4 (compound 5) is a potent inhibitor of KRAS with IC50s of 0.37 nM (Kras G12C), 0.19 nM (Kras G12V), respectively[1].
Related Catalog
Target

IC50: 0.37 nM (Kras G12C), 0.19 nM (Kras G12V)

References

[1]. Chen Y, et al. Synthesis of Mutant KRAS modulators treating neoplastic, autoimmune diseases, and inflammatory disorders. World Intellectual Property Organization, WO2022271823 A1 2022-12-29.

 Chemical & Physical Properties

Molecular Formula C36H34F2N6O3
Molecular Weight 636.69
InChIKey YUFVOCUAYXHCEL-UHFFFAOYSA-N
SMILES C#Cc1c(F)ccc2cc(O)cc(-c3ncc4c(N5CC6CCC(C5)N6C(=O)C=C)nc(OCC56CCCN5CCC6)nc4c3F)c12
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Chemsrc provides pan-KRAS-IN-4(CAS#:2885961-55-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of pan-KRAS-IN-4 are included as well.>> amp version: pan-KRAS-IN-4

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