2885961-55-5

2885961-55-5 structure
2885961-55-5 structure
  • Name: pan-KRAS-IN-4
  • Chemical Name: pan-KRAS-IN-4
  • CAS Number: 2885961-55-5
  • Molecular Formula: C36H34F2N6O3
  • Molecular Weight: 636.69
  • Catalog: Signaling Pathways GPCR/G Protein Ras
  • Create Date: 2023-10-23 13:25:11
  • Modify Date: 2024-01-08 10:44:45
  • pan-KRAS-IN-4 (compound 5) is a potent inhibitor of KRAS with IC50s of 0.37 nM (Kras G12C), 0.19 nM (Kras G12V), respectively[1].

Name pan-KRAS-IN-4
Description pan-KRAS-IN-4 (compound 5) is a potent inhibitor of KRAS with IC50s of 0.37 nM (Kras G12C), 0.19 nM (Kras G12V), respectively[1].
Related Catalog
Target

IC50: 0.37 nM (Kras G12C), 0.19 nM (Kras G12V)

References

[1]. Chen Y, et al. Synthesis of Mutant KRAS modulators treating neoplastic, autoimmune diseases, and inflammatory disorders. World Intellectual Property Organization, WO2022271823 A1 2022-12-29.

Molecular Formula C36H34F2N6O3
Molecular Weight 636.69
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