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2885961-55-5

2885961-55-5 structure

2885961-55-5 structure

Name: pan-KRAS-IN-4
Chemical Name: pan-KRAS-IN-4
CAS Number: 2885961-55-5
Molecular Formula: C₃₆H₃₄F₂N₆O₃
Molecular Weight: 636.69
Catalog: Signaling Pathways GPCR/G Protein Ras
Create Date: 2023-10-23 13:25:11
Modify Date: 2025-09-18 11:56:28
pan-KRAS-IN-4 (compound 5) is a potent inhibitor of KRAS with IC50s of 0.37 nM (Kras G12C), 0.19 nM (Kras G12V), respectively[1].

Name	pan-KRAS-IN-4

Description	pan-KRAS-IN-4 (compound 5) is a potent inhibitor of KRAS with IC50s of 0.37 nM (Kras G12C), 0.19 nM (Kras G12V), respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Ras
Target	IC50: 0.37 nM (Kras G12C), 0.19 nM (Kras G12V)
References	[1]. Chen Y, et al. Synthesis of Mutant KRAS modulators treating neoplastic, autoimmune diseases, and inflammatory disorders. World Intellectual Property Organization, WO2022271823 A1 2022-12-29.

Molecular Formula	C₃₆H₃₄F₂N₆O₃
Molecular Weight	636.69

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