EP12

Modify Date: 2025-08-30 00:38:40

EP12 Structure
EP12 structure
Common Name EP12
CAS Number 2882916-73-4 Molecular Weight 427.47
Density N/A Boiling Point N/A
Molecular Formula C26H22FN3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EP12


EP12 is a c-Myc inhibitor. EP12 is a c-Myc G4 stabilizer. EP12 induces apoptosis and DNA damage in multiple myeloma cells. EP12 disrupts the nuclear translocation of P65/P50 by interfering with the NF-κB signaling pathway. EP12 inhibits multiple myeloma growth[1].

 Names

Name EP12

 EP12 Biological Activity

Description EP12 is a c-Myc inhibitor. EP12 is a c-Myc G4 stabilizer. EP12 induces apoptosis and DNA damage in multiple myeloma cells. EP12 disrupts the nuclear translocation of P65/P50 by interfering with the NF-κB signaling pathway. EP12 inhibits multiple myeloma growth[1].
Related Catalog
References

[1]. Yao R, et al. Novel c-Myc G4 stabilizer EP12 promotes myeloma cytotoxicity by disturbing NF-κB signaling. Exp Cell Res. 2023 Oct 1;431(1):113759.  

 Chemical & Physical Properties

Molecular Formula C26H22FN3O2
Molecular Weight 427.47
InChIKey QBDKHCSVTPBJGK-UHFFFAOYSA-N
SMILES Cc1cc(C)cc(OCCn2c(-c3cc(-c4ccc(F)cc4)on3)nc3ccccc32)c1
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