EP12

Names

[ CAS No. ]:
2882916-73-4

[ Name ]:
EP12

Biological Activity

[Description]:

EP12 is a c-Myc inhibitor. EP12 is a c-Myc G4 stabilizer. EP12 induces apoptosis and DNA damage in multiple myeloma cells. EP12 disrupts the nuclear translocation of P65/P50 by interfering with the NF-κB signaling pathway. EP12 inhibits multiple myeloma growth[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> Apoptosis >> c-Myc

[References]

[1]. Yao R, et al. Novel c-Myc G4 stabilizer EP12 promotes myeloma cytotoxicity by disturbing NF-κB signaling. Exp Cell Res. 2023 Oct 1;431(1):113759.  

Chemical & Physical Properties

[ Molecular Formula ]:
C26H22FN3O2

[ Molecular Weight ]:
427.47


Related Compounds

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