8-prenylkaempferol
8-prenylkaempferol structure
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Common Name | 8-prenylkaempferol | ||
|---|---|---|---|---|
| CAS Number | 28610-31-3 | Molecular Weight | 354.353 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 605.7±55.0 °C at 760 mmHg | |
| Molecular Formula | C20H18O6 | Melting Point | 220-222°C | |
| MSDS | N/A | Flash Point | 219.2±25.0 °C | |
Use of 8-prenylkaempferolDesmethylicaritin is a phytoestrogenic molecule, has inducible effect on directional differentiation of embryonic stem cells into cardiomyocytes. Desmethylicaritin also suppresses adipogenesis via Wnt/β-catenin signaling pathway[1][2]. |
| Name | 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)chromen-4-one |
|---|---|
| Synonym | More Synonyms |
| Description | Desmethylicaritin is a phytoestrogenic molecule, has inducible effect on directional differentiation of embryonic stem cells into cardiomyocytes. Desmethylicaritin also suppresses adipogenesis via Wnt/β-catenin signaling pathway[1][2]. |
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| Related Catalog | |
| In Vitro | 去甲基菌素是血清中淫羊藿类黄酮的生物活性代谢产物[1]。 去甲基甘草素 (0.1, 1, 10 μM; 48 h) 以剂量依赖的方式抑制 3T3-L1 细胞的脂肪生成并抑制脂肪生成过程中的克隆扩增[1]。 去甲基孢菌素 (10 μM; 48 h) 不影响 CCAAT/增强子结合蛋白 δ 和 β 的 mRNA 的表达，但降低了 CCAAT/增强子结合蛋白 α、过氧化物酶体增殖物激活受体 γ、脂肪细胞脂质结合蛋白和脂蛋白脂肪酶的mRNA表达[1]。 去甲基孢菌素 (10 μM; 2、4、6、10 d) 增加了细胞质和细胞核中 β-catenin 的蛋白表达，免疫荧光结果证实去甲基化菌素增加了 β-catenin 的核转运[1]。 |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 605.7±55.0 °C at 760 mmHg |
| Melting Point | 220-222°C |
| Molecular Formula | C20H18O6 |
| Molecular Weight | 354.353 |
| Flash Point | 219.2±25.0 °C |
| Exact Mass | 354.110352 |
| PSA | 111.13000 |
| LogP | 4.15 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.700 |
| InChIKey | NADCVNHITZNGJU-UHFFFAOYSA-N |
| SMILES | CC(C)=CCc1c(O)cc(O)c2c(=O)c(O)c(-c3ccc(O)cc3)oc12 |
| Storage condition | Refrigerator |
| Hazard Codes | Xi |
|---|---|
| HS Code | 2914501900 |
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8-prenylkaempferol CAS#:28610-31-3 |
| Literature: Zhang, Nan; Calderwood, Stuart K. Patent: US2008/214844 A1, 2008 ; Location in patent: Page/Page column 2 ; |
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~82%
8-prenylkaempferol CAS#:28610-31-3 |
| Literature: Fukai, Toshio; Nomura, Taro Heterocycles, 1992 , vol. 34, # 6 p. 1213 - 1225 |
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~73%
8-prenylkaempferol CAS#:28610-31-3 |
| Literature: Daskiewicz, Jean-Baptiste; Depeint, Flore; Viornery, Lionel; Bayet, Christine; Comte-Sarrazin, Geraldine; Comte, Gilles; Gee, Jennifer M.; Johnson, Ian T.; Ndjoko, Karine; Hostettmann, Kurt; Barron, Denis Journal of Medicinal Chemistry, 2005 , vol. 48, # 8 p. 2790 - 2804 |
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8-prenylkaempferol CAS#:28610-31-3 |
| Literature: Yamamoto, Hirobumi; Senda, Masayuki; Inoue, Kenichiro Phytochemistry, 2000 , vol. 54, # 7 p. 649 - 655 |
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8-prenylkaempferol CAS#:28610-31-3 |
| Literature: Fukai, Toshio; Nomura, Taro Heterocycles, 1992 , vol. 34, # 6 p. 1213 - 1225 |
|
~%
8-prenylkaempferol CAS#:28610-31-3 |
| Literature: Fukai, Toshio; Nomura, Taro Heterocycles, 1992 , vol. 34, # 6 p. 1213 - 1225 |
|
~%
8-prenylkaempferol CAS#:28610-31-3 |
| Literature: Daskiewicz, Jean-Baptiste; Depeint, Flore; Viornery, Lionel; Bayet, Christine; Comte-Sarrazin, Geraldine; Comte, Gilles; Gee, Jennifer M.; Johnson, Ian T.; Ndjoko, Karine; Hostettmann, Kurt; Barron, Denis Journal of Medicinal Chemistry, 2005 , vol. 48, # 8 p. 2790 - 2804 |
|
~%
8-prenylkaempferol CAS#:28610-31-3 |
| Literature: Fukai, Toshio; Nomura, Taro Heterocycles, 1992 , vol. 34, # 6 p. 1213 - 1225 |
| HS Code | 2914501900 |
|---|---|
| Summary | 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
| 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one |
| Noranhydroicaritin |
| 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-chromen-4-one |
| 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)- |
| 4'-Desmethylicaritin |
| Desmethyl Icaritin |
| De-O-methylanhydroicaritin |
| 8-Prenylkaempferol |
| desmethylanhydroicaritin |