NK3R-IN-1

Modify Date: 2025-09-19 14:11:46

NK3R-IN-1 structure	Common Name	NK3R-IN-1
	CAS Number	2854331-14-7	Molecular Weight	357.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₆FN₅OS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of NK3R-IN-1

NK3R-IN-1 (compound 16x), a imidazolepiperazine derivative, is an orally active Neurokinin Receptor NK3R inhibitor. NK3R-IN-1 decreases blood luteinizing hormone levels in ovariectomy (OVX) model[1].

Name	NK3R-IN-1

Description	NK3R-IN-1 (compound 16x), a imidazolepiperazine derivative, is an orally active Neurokinin Receptor NK3R inhibitor. NK3R-IN-1 decreases blood luteinizing hormone levels in ovariectomy (OVX) model[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
References	[1]. Ye L, et al. Synthesis and evaluation of piperazinotriazoles. Discovery of a potent and orally bioavailable neurokinin-3 receptor inhibitor. Eur J Med Chem. 2023 Sep 5;257:115486.

Molecular Formula	C₁₇H₁₆FN₅OS
Molecular Weight	357.41

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