2854331-14-7

2854331-14-7 structure

2854331-14-7 structure

Name: NK3R-IN-1
Chemical Name: NK3R-IN-1
CAS Number: 2854331-14-7
Molecular Formula: C₁₇H₁₆FN₅OS
Molecular Weight: 357.41
Catalog: Signaling Pathways GPCR/G Protein Neurokinin Receptor
Create Date: 2023-09-20 22:52:49
Modify Date: 2024-01-22 18:10:01
NK3R-IN-1 (compound 16x), a imidazolepiperazine derivative, is an orally active Neurokinin Receptor NK3R inhibitor. NK3R-IN-1 decreases blood luteinizing hormone levels in ovariectomy (OVX) model[1].

Name	NK3R-IN-1

Description	NK3R-IN-1 (compound 16x), a imidazolepiperazine derivative, is an orally active Neurokinin Receptor NK3R inhibitor. NK3R-IN-1 decreases blood luteinizing hormone levels in ovariectomy (OVX) model[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
References	[1]. Ye L, et al. Synthesis and evaluation of piperazinotriazoles. Discovery of a potent and orally bioavailable neurokinin-3 receptor inhibitor. Eur J Med Chem. 2023 Sep 5;257:115486.

Molecular Formula	C₁₇H₁₆FN₅OS
Molecular Weight	357.41