RDN2150

RDN2150 Structure
RDN2150 structure
 Common Name RDN2150
CAS Number 2839429-51-3 Molecular Weight 577.03
Density N/A Boiling Point N/A
Molecular Formula C28H29ClN8O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RDN2150


RDN2150 (Compound 25) is a ZAP-70 inhibitor (IC50: 14.6 nM). RDN2150 covalently binds to the C346 residue of ZAP-70. RDN2150 inhibits the expression of CD25 and CD69, and inhibits CD4+ T cell activation. RDN2150 can be used for research of psoriasis[1].

 Names

Name RDN2150

 RDN2150 Biological Activity

Description RDN2150 (Compound 25) is a ZAP-70 inhibitor (IC50: 14.6 nM). RDN2150 covalently binds to the C346 residue of ZAP-70. RDN2150 inhibits the expression of CD25 and CD69, and inhibits CD4+ T cell activation. RDN2150 can be used for research of psoriasis[1].
Related Catalog
Target

14.6 nM (ZAP-70)[1]

References

[1]. Rao D, et al. Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis. J Med Chem. 2023 Aug 18.  

 Chemical & Physical Properties

Molecular Formula C28H29ClN8O4
Molecular Weight 577.03
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Chemsrc provides RDN2150(CAS#:2839429-51-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of RDN2150 are included as well.>> amp version: RDN2150

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