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2839429-51-3

2839429-51-3 structure
2839429-51-3 structure
  • Name: RDN2150
  • Chemical Name: RDN2150
  • CAS Number: 2839429-51-3
  • Molecular Formula: C28H29ClN8O4
  • Molecular Weight: 577.03
  • Catalog: Research Areas Inflammation/Immunology
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  • RDN2150 (Compound 25) is a ZAP-70 inhibitor (IC50: 14.6 nM). RDN2150 covalently binds to the C346 residue of ZAP-70. RDN2150 inhibits the expression of CD25 and CD69, and inhibits CD4+ T cell activation. RDN2150 can be used for research of psoriasis[1].

Name RDN2150
Description RDN2150 (Compound 25) is a ZAP-70 inhibitor (IC50: 14.6 nM). RDN2150 covalently binds to the C346 residue of ZAP-70. RDN2150 inhibits the expression of CD25 and CD69, and inhibits CD4+ T cell activation. RDN2150 can be used for research of psoriasis[1].
Related Catalog
Target

14.6 nM (ZAP-70)[1]

References

[1]. Rao D, et al. Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis. J Med Chem. 2023 Aug 18.  

Molecular Formula C28H29ClN8O4
Molecular Weight 577.03
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