5-Hydroxy-1-tetralone

Modify Date: 2025-08-20 11:12:33

5-Hydroxy-1-tetralone Structure
5-Hydroxy-1-tetralone structure
 Common Name 5-Hydroxy-1-tetralone
CAS Number 28315-93-7 Molecular Weight 162.185
Density 1.2±0.1 g/cm3 Boiling Point 325.3±31.0 °C at 760 mmHg
Molecular Formula C10H10O2 Melting Point 206-209 °C(lit.)
MSDS Chinese USA Flash Point 138.1±17.4 °C

 Use of 5-Hydroxy-1-tetralone


5-hydroxy-1-tetralone can be used as a fluorescent labeling reagent for the determination of glycosphingolipid from biological samples[1].

 Names

Name 5-hydroxy-3,4-dihydro-2H-naphthalen-1-one
Synonym More Synonyms

 5-Hydroxy-1-tetralone Biological Activity

Description 5-hydroxy-1-tetralone can be used as a fluorescent labeling reagent for the determination of glycosphingolipid from biological samples[1].
Related Catalog
Target

Fluorescent labeling[1]

References

[1]. Watanabe K, et al. Fluorometric detection of glycosphingolipids on thin-layer chromatographic plates. J Lipid Res. 1995 Aug;36(8):1848-55.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 325.3±31.0 °C at 760 mmHg
Melting Point 206-209 °C(lit.)
Molecular Formula C10H10O2
Molecular Weight 162.185
Flash Point 138.1±17.4 °C
Exact Mass 162.068085
PSA 37.30000
LogP 2.34
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.603
InChIKey YPPZCRZRQHFRBH-UHFFFAOYSA-N
SMILES O=C1CCCc2c(O)cccc21

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S22-S24/25-S37/39-S26
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2914400090

 Synthetic Route

1,5-Dihydroxynaphthalene structure

1,5-Dihydroxyna...

CAS#:83-56-7

~86%

5-Hydroxy-1-tetralone Structure

5-Hydroxy-1-tet...

CAS#:28315-93-7

Literature: Ostashevskaya; Koltunov; Repinskaya Russian Journal of Organic Chemistry, 2000 , vol. 36, # 10 p. 1474 - 1477
5-methoxy-3,4-dihydro-2H-naphthalen-1-one structure

5-methoxy-3,4-d...

CAS#:33892-75-0

~87%

5-Hydroxy-1-tetralone Structure

5-Hydroxy-1-tet...

CAS#:28315-93-7

Literature: Valderrama; Pessoa-Mahana; Tapia Synthetic Communications, 1992 , vol. 22, # 4 p. 629 - 639
1,2,3,4-TETRAHYDRO-1,5-NAPHTHALENEDIOL structure

1,2,3,4-TETRAHY...

CAS#:40771-26-4

~97%

5-Hydroxy-1-tetralone Structure

5-Hydroxy-1-tet...

CAS#:28315-93-7

Literature: Krohn, Karsten; Khanbabaee, Karamali; Rieger, Hagen Chemische Berichte, 1990 , vol. 123, # 6 p. 1357 - 1364
4,5-Dihydrobenzo[b]oxepin-2(3H)-one structure

4,5-Dihydrobenz...

CAS#:3041-17-6

~7%

4-(2-Hydroxyphenyl)butanoic acid structure

4-(2-Hydroxyphe...

CAS#:35387-19-0

5-Hydroxy-1-tetralone Structure

5-Hydroxy-1-tet...

CAS#:28315-93-7

Literature: Cambie, Richard C.; Mitchell, Lorna H.; Rutledge, Peter S. Australian Journal of Chemistry, 1998 , vol. 51, # 12 p. 1167 - 1174
3,4-Dihydronaphthalen-1(2H)-one structure

3,4-Dihydronaph...

CAS#:529-34-0

~33%

7-Hydroxy-1-tetralone structure

7-Hydroxy-1-tet...

CAS#:22009-38-7

5-Hydroxy-1-tetralone Structure

5-Hydroxy-1-tet...

CAS#:28315-93-7

5,8-dihydroxy-1-tetralone structure

5,8-dihydroxy-1...

CAS#:1077-69-6

Literature: Gesson, Jean-Pierre; Jacquesy, Jean-Claude; Jouannetaud, Marie-Paule; Morellet, Guy Tetrahedron Letters, 1983 , vol. 24, # 30 p. 3095 - 3098
acetic acid,5,6,7,8-tetrahydronaphthalen-1-ol structure

acetic acid,5,6...

CAS#:91028-13-6

~%

5-Hydroxy-1-tetralone Structure

5-Hydroxy-1-tet...

CAS#:28315-93-7

Literature: Momose; Ohkura Pharmaceutical Bulletin, 1956 , vol. 4, p. 209
1,5-Naphthalenedione,octahydro- structure

1,5-Naphthalene...

CAS#:13913-82-1

~%

5-Hydroxy-1-tetralone Structure

5-Hydroxy-1-tet...

CAS#:28315-93-7

Literature: Hudson; Robinson Journal of the Chemical Society, 1942 , p. 691
5-Hydroxytetralin structure

5-Hydroxytetralin

CAS#:529-35-1

~%

5-Hydroxy-1-tetralone Structure

5-Hydroxy-1-tet...

CAS#:28315-93-7

Literature: Momose; Ohkura Pharmaceutical Bulletin, 1956 , vol. 4, p. 209

 Customs

HS Code 2914400090
Summary 2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Articles4

More Articles
Simple and selective assay of 4-hydroxymephenytoin in human urine using solid-phase extraction and high-performance liquid chromatography with electrochemical detection and its preliminary application to phenotyping test.

J. Chromatogr. B, Biomed. Appl. 676(1) , 87-94, (1996)

A simple and selective HPLC method for the determination of 4-hydroxymephenytoin (4-OH-M) in human urine, using a controlled potential coulometric detector equipped with a dual working electrode cell ...

Fluorometric detection of glycosphingolipids on thin-layer chromatographic plates.

J. Lipid Res. 36(8) , 1848-55, (1995)

A microdetection system for glycosphingolipid analysis has been developed using 5-hydroxy-1-tetralone as the fluorescent labeling reagent. The reagents in H2SO4 permit the fluorometric detection of ac...

Studies on Quinones. Part 22.'Synthesis of 1-Benzazepine-6, 9-Quinone Derivatives. Valderrama JA, et al.

Synth. Commun. 22(4) , 629-40, (1992)

 Synonyms

5-hydroxy-1-oxotetraline
5-hydroxy-1,2,3,4-tetrahydro-1-naphthalenone
1-Tetralon-5-ol
EINECS 248-958-0
5-Hydroxy-3,4-dihydronaphthalen-1(2H)-one
1-hydroxy-5-oxo-5,6,7,8-tetrahydronaphthalene
1(2H)-Naphthalenone,3,4-dihydro-5-hydroxy
1(2H)-Naphthalenone, 3,4-dihydro-5-hydroxy-
5-hydroxy-2,3,4-trihydronaphthalen-1-one
3,4-Dihydro-5-hydroxy-1(2H)-naphthalenone
1,2,3,4-Tetrahydro-5-hydroxynaphthalen-1-one
5-Hydroxy-3,4-dihydro-1(2H)-naphthalenone
5-Hydroxy-1-Tetralone
5-Hydroy-1-tetraione
5-hydroxy-3,4-dihydronaphthalene-1(2H)-one
5-hydroxy-1,2,3,4-tetrahydronaphthalen-1-one
MFCD00001693
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