L-Glyceric acid

Modify Date: 2024-01-07 15:56:26

L-Glyceric acid Structure
L-Glyceric acid structure
Common Name L-Glyceric acid
CAS Number 28305-26-2 Molecular Weight 106.07700
Density N/A Boiling Point N/A
Molecular Formula C3H6O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of L-Glyceric acid


L-Glyceric acid is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid excretion to distinguish PH1 from PH2[1][2].

 Names

Name D-glyceric acid
Synonym More Synonyms

 L-Glyceric acid Biological Activity

Description L-Glyceric acid is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid excretion to distinguish PH1 from PH2[1][2].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Primary hyperoxaluria type 2 (PH2), also called L-glyceric aciduria. The metabolic defect is due to deficiencies of D-glycerate dehydrogenase and glyoxylate reductase, leading to excretion of L-Glyceric acid, and L-Glyceric acid is the cornerstone for the diagnosis of PH2[1][2].
References

[1]. Mohamed S Rashed, et al. Chiral liquid chromatography tandem mass spectrometry in the determination of the configuration of glyceric acid in urine of patients with D-glyceric and L-glyceric acidurias. Biomed Chromatogr. 2002 May;16(3):191-8.

[2]. Bernd Hoppe, et al. A United States survey on diagnosis, treatment, and outcome of primary hyperoxaluria. Pediatr Nephrol. 2003 Oct;18(10):986-91.

 Chemical & Physical Properties

Molecular Formula C3H6O4
Molecular Weight 106.07700
Exact Mass 106.02700
PSA 77.76000

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

(2s)-2,3-dihydroxypropanoic acid
l-glyceric acid