L-Glyceric acid sodium

Modify Date: 2024-01-09 12:07:24

L-Glyceric acid sodium Structure
L-Glyceric acid sodium structure
Common Name L-Glyceric acid sodium
CAS Number 146298-95-5 Molecular Weight 128.06
Density N/A Boiling Point N/A
Molecular Formula C3H5NaO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of L-Glyceric acid sodium


L-Glyceric acid sodium is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid sodium can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid sodium excretion to distinguish PH1 from PH2[1][2].

 Names

Name L-Glyceric acid sodium

 L-Glyceric acid sodium Biological Activity

Description L-Glyceric acid sodium is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid sodium can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid sodium excretion to distinguish PH1 from PH2[1][2].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Primary hyperoxaluria type 2 (PH2), also called L-glyceric aciduria. The metabolic defect is due to deficiencies of D-glycerate dehydrogenase and glyoxylate reductase, leading to excretion of L-Glyceric acid, and L-Glyceric acid is the cornerstone for the diagnosis of PH2[1][2].
References

[1]. Mohamed S Rashed, et al. Chiral liquid chromatography tandem mass spectrometry in the determination of the configuration of glyceric acid in urine of patients with D-glyceric and L-glyceric acidurias. Biomed Chromatogr. 2002 May;16(3):191-8.

[2]. Bernd Hoppe, et al. A United States survey on diagnosis, treatment, and outcome of primary hyperoxaluria. Pediatr Nephrol. 2003 Oct;18(10):986-91.

 Chemical & Physical Properties

Molecular Formula C3H5NaO4
Molecular Weight 128.06