AB-729 sodium

Modify Date: 2024-01-12 19:40:24

AB-729 sodium structure	Common Name	AB-729 sodium
	CAS Number	2826248-50-2	Molecular Weight	16148.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₀₂H₆₄₀F₆N₁₆₂Na₃₈O₃₀₃P₃₈S₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AB-729 sodium

AB-729 sodium is a siRNA specifically designed to inhibit viral replication and reduces HBV antigens[1][2]. AB-729 conjugates to a trimer of N-acetylgalactosamine (GalNAc) ligand that promotes uptake into hepatocytes via the asialoglycoprotein receptor (ASGR).

Name	AB-729 sodium

Description	AB-729 sodium is a siRNA specifically designed to inhibit viral replication and reduces HBV antigens[1][2]. AB-729 conjugates to a trimer of N-acetylgalactosamine (GalNAc) ligand that promotes uptake into hepatocytes via the asialoglycoprotein receptor (ASGR).
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV
References	[1]. Efthymios P Tsounis, et al. Toward a new era of hepatitis B virus therapeutics: The pursuit of a functional cure. World J Gastroenterol. 2021 Jun 7;27(21):2727-2757. [2]. Arbutus Receives Authorization to Proceed with an Investigational New Drug Application (IND) for AB-729, its Proprietary Subcutaneously-Delivered RNAi Agent.

Description

Related Catalog

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> HBV

References

[1]. Efthymios P Tsounis, et al. Toward a new era of hepatitis B virus therapeutics: The pursuit of a functional cure. World J Gastroenterol. 2021 Jun 7;27(21):2727-2757.

[2]. Arbutus Receives Authorization to Proceed with an Investigational New Drug Application (IND) for AB-729, its Proprietary Subcutaneously-Delivered RNAi Agent.

Molecular Formula	C₅₀₂H₆₄₀F₆N₁₆₂Na₃₈O₃₀₃P₃₈S₆
Molecular Weight	16148.44

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AB-729 sodium

Use of AB-729 sodium

Names

AB-729 sodium Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.