2826248-50-2

2826248-50-2 structure

Name: AB-729 sodium
Chemical Name: AB-729 sodium
CAS Number: 2826248-50-2
Molecular Formula: C₅₀₂H₆₄₀F₆N₁₆₂Na₃₈O₃₀₃P₃₈S₆
Molecular Weight: 16148.44
Catalog: Signaling Pathways Anti-infection HBV
Create Date: 2024-01-12 19:40:24
Modify Date: 2024-01-12 19:40:24
AB-729 sodium is a siRNA specifically designed to inhibit viral replication and reduces HBV antigens[1][2]. AB-729 conjugates to a trimer of N-acetylgalactosamine (GalNAc) ligand that promotes uptake into hepatocytes via the asialoglycoprotein receptor (ASGR).

Name	AB-729 sodium

Description	AB-729 sodium is a siRNA specifically designed to inhibit viral replication and reduces HBV antigens[1][2]. AB-729 conjugates to a trimer of N-acetylgalactosamine (GalNAc) ligand that promotes uptake into hepatocytes via the asialoglycoprotein receptor (ASGR).
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV
References	[1]. Efthymios P Tsounis, et al. Toward a new era of hepatitis B virus therapeutics: The pursuit of a functional cure. World J Gastroenterol. 2021 Jun 7;27(21):2727-2757. [2]. Arbutus Receives Authorization to Proceed with an Investigational New Drug Application (IND) for AB-729, its Proprietary Subcutaneously-Delivered RNAi Agent.

Molecular Formula	C₅₀₂H₆₄₀F₆N₁₆₂Na₃₈O₃₀₃P₃₈S₆
Molecular Weight	16148.44