SCAL-266

Modify Date: 2024-11-30 18:04:06

SCAL-266 structure	Common Name	SCAL-266
	CAS Number	2798953-78-1	Molecular Weight	511.54
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₇H₂₈F₃N₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SCAL-266

SCAL-266 is a potent mitochondrial complex I (CI) inhibitor with IC50 of 0.83 μM. SCAL-266 blocks mitochondrial function, inhibits OCR, induces ROS production, and reduces MMP. SCAL-266 displays a considerable antiproliferation effect against oxidative phosphorylation (OXPHOS)-dependent cancer cells[1].

Name	SCAL-266

Description	SCAL-266 is a potent mitochondrial complex I (CI) inhibitor with IC50 of 0.83 μM. SCAL-266 blocks mitochondrial function, inhibits OCR, induces ROS production, and reduces MMP. SCAL-266 displays a considerable antiproliferation effect against oxidative phosphorylation (OXPHOS)-dependent cancer cells[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Yang Zhou, et al. Synthesis and biological evaluation of novel pyrazole amides as potent mitochondrial complex I inhibitors. Eur J Med Chem. 2023 Oct 5;258:115576.

Molecular Formula	C₂₇H₂₈F₃N₅O₂
Molecular Weight	511.54
InChIKey	ODXBKEDGMKYXEZ-UHFFFAOYSA-N
SMILES	Cc1cc(C(=O)Nc2ccc(C(F)(F)F)cc2)nn1Cc1cccc(N2CCN(C(=O)C3CC3)CC2)c1

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SCAL-266

Use of SCAL-266

Names

SCAL-266 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.