2798953-78-1

2798953-78-1 structure

Name: SCAL-266
Chemical Name: SCAL-266
CAS Number: 2798953-78-1
Molecular Formula: C₂₇H₂₈F₃N₅O₂
Molecular Weight: 511.54
Catalog: Research Areas Cancer
Create Date: 2023-09-22 19:37:08
Modify Date: 2024-11-30 18:04:06
SCAL-266 is a potent mitochondrial complex I (CI) inhibitor with IC50 of 0.83 μM. SCAL-266 blocks mitochondrial function, inhibits OCR, induces ROS production, and reduces MMP. SCAL-266 displays a considerable antiproliferation effect against oxidative phosphorylation (OXPHOS)-dependent cancer cells[1].

Name	SCAL-266

Description	SCAL-266 is a potent mitochondrial complex I (CI) inhibitor with IC50 of 0.83 μM. SCAL-266 blocks mitochondrial function, inhibits OCR, induces ROS production, and reduces MMP. SCAL-266 displays a considerable antiproliferation effect against oxidative phosphorylation (OXPHOS)-dependent cancer cells[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Yang Zhou, et al. Synthesis and biological evaluation of novel pyrazole amides as potent mitochondrial complex I inhibitors. Eur J Med Chem. 2023 Oct 5;258:115576.

Molecular Formula	C₂₇H₂₈F₃N₅O₂
Molecular Weight	511.54