ZDLD20
Modify Date: 2025-09-24 11:29:04
ZDLD20 structure
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Common Name | ZDLD20 | ||
|---|---|---|---|---|
| CAS Number | 2762279-02-5 | Molecular Weight | 386.45 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H22N6O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ZDLD20ZDLD20, a β-carboline, is orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 6.51 μM. ZDLD20 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD20 exhibits potent anticancer activity[1]. |
| Name | ZDLD20 |
|---|
| Description | ZDLD20, a β-carboline, is orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 6.51 μM. ZDLD20 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD20 exhibits potent anticancer activity[1]. |
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| Related Catalog | |
| Target |
CDK4/CycD3:6.51 μM (IC50) |
| References |
| Molecular Formula | C22H22N6O |
|---|---|
| Molecular Weight | 386.45 |
| InChIKey | KNMQEDYCAKYYTK-UHFFFAOYSA-N |
| SMILES | CN1CCN(c2ccc(NC(=O)c3nccc4c3[nH]c3ccccc34)nc2)CC1 |